Anogenital warts (condylomas) are caused by human papillomavirus (HPV) with >90% of the lesions caused by genotypes 6 & 11.
Patients who present with visible warts may also be infected with high-risk HPVs (eg types 16 & 18) which can cause subclinical lesions that are associated with intraepithelial neoplasia, cervical cancer and anogenital cancer.
Many HPV infections are subclinical, transient, and clear spontaneously within 12 months but may also remain latent and reactivate after several years.
  1. O'Mahony C. Genital warts: current and future management options. Am J Clin Dermatol. 2005;6(4):239-243. PMID: 16060711
  2. American Academy of Dermatology Association. Practice management: guidelines of care for warts: human papillomavirus. J Am Acad Dermatol. 1995;32:98-103
  3. Centers for Disease Control and Prevention, Workowski KA, Berman SM. HPV infection and genital warts. Sexually transmitted diseases treatment guidelines 2006. MMWR. 2006;55(RR-11):62-67. PMID: 16888612
  4. Darvelle T. Genital warts. Pediatr Rev. 1999 Aug;20(8):271-272. PMID: 10429146
  5. Lipke MM. An armamentarium of warts treatments. Clin Med Res. 2006 Dec;4(4):273-293. PMID: 17210977
  6. Kodner CM, Nasraty S. Management of genital warts. Am Fam Physician. 2004 Dec;70(12):2335-2342. PMID: 15617297
  7. Von Krogh G, Lacey CJ, Gross G, et al. European course on HPV associated pathology: guidelines for primary care physicians for the diagnosis and management of anogenital warts. Sex Transm Infect. 2000 Jun;76(3):162-168. http://www.ncbi.nlm.nih.gov/pubmed/?term=10961190. PMID: 10961190
  8. Woodward C, Fisher MA. Drug treatment of common STDs: part II. Vaginal infections, pelvic inflammatory disease and genital warts. Am Fam Physician. 1999 Oct;60(6):1716-1722. http://www.ncbi.nlm.nih.gov/pubmed/?term=10537386. PMID: 10537386
  9. MedWormhttp://www.medworm.com/rss/index.php/Dermatology/12/http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology.xml
  10. MedWormhttp://www.medworm.com/rss/index.php/OBGYN/29/http://www.medworm.com/rss/medicalfeeds/specialities/OBGYN.xml
  11. Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases. 2002 national guideline for the management of anogenital warts. London, UK: Association of Genitourinary Medicine (AGUM), Medical Society for the Study of Venereal Diseases (MSSVD). http://www.guideline.gov. 2002.
  12. Bauer H for National Network of STD/HIV Prevention Training Center. Genital HPV infection. www.stdhivtraining.org. 2004.
  13. Professional Advisory Board of the Australia and New Zealand HPV Project. Guidelines for the management of genital HPV infection in Australia and New Zealand. 5th ed. http://www.hpv.org.nz. 2007.
  14. Professional Advisory Board of the New Zealand HPV Project. Guidelines for the management of genital HPV infection in New Zealand. 7th ed. http://www.hpv.org.nz. 2013.
  15. Clinical Effectiveness Group, British Association for Sexual Health and HIV (CEG/BASHH). United Kingdom national guideline on the management of anogenital warts. British Association for Sexual Health and HIV (BASHH). http://www.bashh.org. 2007.
  16. Rinker MH. Warts, nongenital. eMedicine. http://emedicine.com. Sep 2005.
  17. Lazaro N. Sexually transmitted infections in primary care 2013 (RCGP/BASHH). Royal College of General Practitioners. http://www.rcgp.org.uk. 2013. Accessed 30 May 2014.
  18. Lacey CJ, Woodhall SC, Wikstrom A, et al. 2012 European guideline for the management of anogenital warts. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):e263-270. doi: 10.1111/j.1468-3083.2012.04493.x. Accessed 24 Jul 2014. PMID: 2409368
  19. Carusi DA. Patient education: genital warts in women (beyond the basics). UpToDate. https://www.uptodate.com. 19 May 2017.
  20. Centers for Disease Control and Prevention. 2015 Sexually transmitted diseases treatment guidelines. Anogenital warts. CDC. https://www.cdc.gov. 04 Jun 2015.
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