vitiligo
VITILIGO
Vitiligo is an acquired, often familial, melanocytopenic disorder that produces focal depigmentation of the skin.
About half of the patients has onset of lesion before the age of 20.
It is a progressive disease wherein spontaneous repigmentation may occur within 6 months.
Precipitating factors include emotional stress, sunburn, chemical exposure, skin trauma, inflammation, irritation or rash that may precede the lesions by 2-3 months.
Lesions are white-colored macules or patches with well-defined borders and otherwise normal skin surface.

Surgical Intervention

Should only be used in non-progressive, small areas of inactive vitiligo

  • Eg epidermal blister grafting, autologous mini punch grafting, ultrathin epidermal sheet grafting, micropigmentation (tattooing), etc
  • May be an option if topical steroids or photochemotherapy fail to repigment
    • Surgery is usually limited to patients who have segmented or localized disease
    • May be used in some generalized patients
  • The following areas tend not to repigment well:
    • Forehead, hairline, dorsal fingers & ankles
  • Follow surgery w/ phototherapy

Editor's Recommendations
Most Read Articles
Jairia Dela Cruz, 24 Jan 2017
The likelihood of developing atopic dermatitis and food sensitization may be low among children with habitual consumption of yogurt products in infancy, according to a recent study.
12 Dec 2017
The use of oral antidepressants appears to have beneficial effects on patients with chronic pruritus not responding to topical treatment and oral antihistamines, particularly those with uremic pruritus, cholestatic pruritus or paraneoplastic pruritus, according to a recent study.
Gayle Fischer, 01 Jun 2014

Acute vulvovaginal candidiasis (VVC) is common and usually easily treated but some women develop chronic symptoms that do not respond to conventional anti-Candida treatment. Recently proposed diagnostic criteria may help clinicians identify women with chronic VVC. Evidence is mounting that it represents a hypersensitivity response to commensal Candida spp. It usually responds to long-term antifungal treatment.

21 Dec 2017
Speedy treatment of stage I melanoma is likely to result in improved outcomes, suggests a recent study.