vitiligo
VITILIGO
Vitiligo is an acquired, often familial, melanocytopenic disorder that produces focal depigmentation of the skin.
About half of the patients has onset of lesion before the age of 20.
It is a progressive disease wherein spontaneous repigmentation may occur within 6 months.
Precipitating factors include emotional stress, sunburn, chemical exposure, skin trauma, inflammation, irritation or rash that may precede the lesions by 2-3 months.
Lesions are white-colored macules or patches with well-defined borders and otherwise normal skin surface.
  1. Al-Khawajah MM. Photochemotherapy for vitiligo: seven years experience at a university hospital. Ann Saudi Med. 1997;17:175-178. PMID: 17377425
  2. American Academy of Dermatology Association. Practice management: guidelines of care for phototherapy and photochemotherapy. J Am Acad Dermatol. 1994;31:643-648. PMID: 8089291
  3. American Academy of Dermatology Association. Practice management: guidelines of care of vitiligo. J Am Acad Dermatol. 1996;35:620-626
  4. Halder RM, Young CM. New and emerging therapies for vitiligo. Dermatol Clin. 2000;18:79-89. PMID: 10626114
  5. Kovacs SO. Vitiligo. J Am Acad Dermatol. 1998;38:647-666. PMID: 9591808
  6. Grimes PE, Sorano T, Dytoc MT. Topical tacrolimus for repigmentation of vitiligo. J Am Acad Dermatol. 2002;47:789-791. PMID: 12399778
  7. Natta R, Smosak T, Wisuttida, et al. Narrowband ultraviolet B radiation therapy for recalcitrant vitiligo in Asians. J Am Acad Dermatol. 2003;49:473-476. PMID: 12963911
  8. Lepe V, Moncada B, Castanedo-Cazares JP, et al. A double- blind randomize trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo. Arch dermatol. 2003;139:581-585. PMID: 12756094
  9. Menchini G, Tsoureli-Nikita E, Hercogova J. Narrow-band UV- B microphototherapy: a new treatment for vitiligo. J Eur Acad Dermatol. 2003;17:171-177. PMID: 12705746
  10. Spencer JM, Nossa R, Ajmeria J. Treatment of vitiligo with the 308-nm excimer laser: a pilot study. J Am Dermatol. 2002;46:727-731. PMID: 12004315
  11. Habif TP. Light-related diseases and disorders of pigmentation. Clinical dermatology: a color guide to diagnosis and therapy. 3rd ed: Mosby; 1996
  12. Su R. Vitiligo. In: Lo KK, Chong LY, Tang YM. Handbook of dermatology & venereology: social hygiene handbook. 2nd ed. Western District, Hong Kong: Hygiene Service, Dept of Health; 1997
  13. MedWorm http://www.medworm.com/rss/index.php/Dermatology/12/ http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology-News.xml
  14. Health information. A service of the US National Library of Medicine and the National Institutes of Health. Drug information: Trioxsalen (systemic);Thomson Micromedex 2003. Medline Plus. http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202580.htm. Accessed 18 Jul 2003
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Natalia Reoutova, 07 Jan 2020

A prospective cohort study of mothers taking antiepileptic drugs (AEDs) and their breastfed infants has found substantially lower AED concentrations in infant vs maternal blood, with nearly half of all obtained AED concentrations in nursing infants being less than the lower limit of quantification (LLoQ).

5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.