vitiligo
VITILIGO
Vitiligo is an acquired, often familial, melanocytopenic disorder that produces focal depigmentation of the skin.
About half of the patients has onset of lesion before the age of 20.
It is a progressive disease wherein spontaneous repigmentation may occur within 6 months.
Precipitating factors include emotional stress, sunburn, chemical exposure, skin trauma, inflammation, irritation or rash that may precede the lesions by 2-3 months.
Lesions are white-colored macules or patches with well-defined borders and otherwise normal skin surface.

Follow Up

Nonsegmental Vitiligo

  • NSV patients on narrow band UVB therapy should be reassessed on the 3rd & 6th mth of therapy
  • If still w/ disease progression after 3 mth of narrow band UVB therapy w/ topical steroid/calcineurin inhibitor therapy, consider switching to systemic corticosteroid therapy
    • After 3-6 mth, consider surgical interventions if disease is stable but w/o repigmentation, or depigmentation therapy if w/o repigmentation & w/ Koebner phenomenon
    • After 9 mth of narrow band UVB treatment, consider surgical interventions if disease is stable but repigmentation stopped

Segmental Vitiligo

  • Reassess patients on topical steroids & calcineurin inhibitors on the 6th mth of therapy
Editor's Recommendations
Most Read Articles
Pearl Toh, 15 Jul 2019
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from the large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
15 Jul 2019
Fluticasone, swallowed from a multidose inhaler, and oral viscous budesonide slurry have comparable efficacies as initial treatment for eosinophilic oesophagitis, a recent study has found.
Yesterday
Health-related quality of life (HRQoL) among patients with kidney stone is worse in those who are young and female than those who are older and male, according to a recent study. Non-Caucasian patients also have a lower HRQoL.
Tristan Manalac, 2 days ago
In patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI), admission Killip classification and creatinine and troponin levels are important cardiac mortality predictors, according to a recent Singapore study.