Varicella, also known as chickenpox, is a self-limited benign disease
caused by primary varicella-zoster virus (VZV) infection characterized
by fever, malaise, and generalized pruritic vesicular rash.
The average incubation period is 14-16 days. It is transmitted via
direct contact with vesicular fluid or inhalation of aerosolized
respiratory secretions or via droplet route during face-to-face contact.
Hallmark sign is pruritic rash that begins in the scalp and face which eventually spreads to the trunks and extremities.
Children under 2 years who received the measles-mumps-rubella-varicella (MMRV) vaccine as a second measles-containing vaccine (MCV) following an MMR vaccine did not have an elevated risk of febrile seizures (FSs), according to an Australian study. The introduction of the MMRV vaccine also increased MCV coverage in Australia.
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The angiotensin receptor blocker (ARB) losartan did not improve inflammation, T-cell immune recovery, or fibrotic activity among older persons living with HIV (PLHIV) and viral suppression, according to data presented at CROI 2020.