varicella-zoster%20virus%20infection%20(pediatric)
VARICELLA-ZOSTER VIRUS INFECTION (PEDIATRIC)
Varicella, also known as chickenpox, is a self-limited, benign disease caused by primary varicella-zoster virus (VZV) infection characterized by fever, malaise, and generalized pruritic vesicular rash.
The average incubation period is 14-16 days. It is transmitted via direct contact with vesicular fluid or inhalation of aerosolized respiratory secretions or via droplet route during face to face contact.
Hallmark sign is pruritic rash that begins in the scalp and face which eventually spreads to the trunks and extremities.

Varicella-Zoster Virus Infection (Pediatric) References

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  3. Chen TM, George S, Woodruff CA, et al. Clinical manifestations of varicella-zoster virus infection. Derm Clin. 2002 Apr;20(2):237-282. PMID: 12120440
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  11. College of Paediatrics, Academy of Medicine Malaysia. Malaysian immunisation manual. Malaysia: College of Paediatrics, Academy of Medicine Malaysia; 2001.
  12. MedWorm http://www.medworm.com/rss/index.php/Dermatology/12/ http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology-News.xml
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  15. Centers for Disease Control and Prevention. Recommended immunization schedules for persons aged 0 through 18 years - United States, 2015. Centers for Disease Control and Prevention website. http://www.cdc.gov/vaccines/schedules/downloads/child/0-18yrs-child-combined-schedule.pdf. Jan 2015.
  16. Centers for Disease Control and Prevention (CDC). Updated recommendations for use of VariZIG--United States, 2013. MMWR Morb Mortal Wkly Rep. 2013 Jul;62(28):574-576. http://www.cdc.gov/mmwr/pdf/wk/mm6228.pdf. PMID: 23863705
  17. Hales CM, Harpaz R, Ortega-Sanchez I, Bialek SR; Centers for Disease Control and Prevention (CDC). Update on recommendations for use of herpes zoster vaccine. MMWR Morb Mortal Wkly Rep. 2014 Aug;63(33):729-731. http://www.cdc.gov/mmwr/pdf/wk/mm6333.pdf. PMID: 25144544
  18. Centers for Disease Control and Prevention (CDC). FDA approval of an extended period for administering VariZIG for postexposure prophylaxis of varicella. MMWR Morb Mortal Wkly Rep. 2012 Mar;61(12):212. http://www.cdc.gov/mmwr/pdf/wk/mm6112.pdf. PMID: 22456121
  19. Centers for Disease Control and Prevention. Varicella vaccination. Centers for Disease Control and Prevention website. http://www.cdc.gov/vaccines/vpd-vac/varicella/default-hcp.htm. Apr 2012.
  20. Myers MG, Seward JF, LaRussa PS. Varicella-zoster virus. In: Kliegman RM, Behrman RE, Jenson HB, et al, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, PA: Saunders, Elsevier Inc; 2007.
  21. Albrecht MA. Treatment of varicella (chickenpox) infection. UptoDate. https://www.uptodate.com/. Mar 2017.
  22. Centers for Disease Control and Prevention. Recommended immunization schedules for persons aged 0 through 18 years - United States, 2017. CDC. https://www.cdc.gov/. Jan 2017.
  23. Robinson CL, Romero JR, Kempe A, Pellegrini C; Advisory Committee on Immunization Practices (ACIP) Child/Adolescent Immunization Work Group. Advisory Committee on Immunization Practices recommended immunization schedule for children and adolescents aged 18 years or younger - United States, 2017. MMWR Morb Mortal Wkly Rep. 2017 Feb;66(5):134-135. doi: 10.15585/mmwr.mm6605e1. PMID: 28182607
  24. Werner RN, Nikkels AF, Marinovic B, et al. European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: Diagnosis. J Eur Acad Dermatol Venereol. 2017 Jan;31(1):9-19. doi: 10.1111/jdv.13995. PMID: 27804172
  25. Werner RN, Nikkels AF, Marinovic B, et al. European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 2: Treatment. J Eur Acad Dermatol Venereol. 2017 Jan;31(1):20-29. doi: 10.1111/jdv.13957. PMID: 27579792
  26. Robinson CL, Romero JR, Kempe A, Pellegrini C, Szilagyi P. Advisory Committee on Immunization Practices recommended immunization schedule for children and adolescents aged 18 years or younger - United States, 2018. MMWR Morb Mortal Wkly Rep. 2018 Feb;67(5):156-157. doi:10.15585/mmwr.mm6705e2. PMID: 29420458
  27. LaRussa PS, Marin M, Gershon AA. Varicella-zoster virus. In: Wilson CB, Nizet V, Maldonado YA, et al. Remington and Klein’s Infectious Diseases of the Fetus and Newborn Infant. 8th. Philadelphia, PA: Elsevier Inc; 2016.
  28. Gershon AA, Marin M, Seward JF. Varicella, measles and mumps. In: Kliegman RM, St Geme JW, Blum NJ, et al. eds. Nelson Textbook of Pediatrics. 21st. Philadelphia, PA: Elsevier, Inc; 2020.
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