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URTICARIA

Urticaria is characterized by the appearance of wheals (hives) and/or angioedema.
The intensity of the pruritus varies but may be severe enough to disrupt sleep, work or school.
It is classified acute if the urticaria has been present for ≤6 weeks and chronic if >6 weeks. It can be spontaneous (no definite triggering factor) or inducible (a specific definite triggering factor is identified).
It can be triggered by immunological or non-immunological mechanism.

Urticaria Signs and Symptoms

Signs and Symptoms

Introduction

Urticaria is a predominantly mast cell-driven disease characterized by the appearance of wheals (hives) and/or angioedema
- Wheals in urticaria are characterized by variable shape and size surrounded by erythema, pruritus or burning sensation, and transient appearance (skin returns to normal within 30 minutes to 24 hours)
- Angioedema in urticaria features sudden prolonged swelling of the lower dermis and subcutis or mucous membranes, produces pain or discomfort, and has slower resolution compared to wheals (up to 72 hours)
Intensity of pruritus varies but may be severe enough to disrupt sleep, work or school

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16 Jun 2021

Furfuryl Palmitate

Expert consensus: Patient profile should guide antihistamine choice in primary care setting

10 Dec 2019

Oral H₁-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.

Antihistamine therapy for allergic rhinitis and urticaria: An Asia-Pacific perspective

01 Nov 2018

The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.