urticaria
URTICARIA
Urticaria is characterized by sudden appearance of wheals and/or angioedema.
The intensity of the pruritus varies but may be severe enough to disrupt sleep, work or school.
It is classified acute if the urticaria has been present for <6 weeks and chronic if >6 weeks. A specific cause is more likely to be identified in acute cases.
It can be triggered by immunological or nonimmunological mechanism.

Introduction

  • Urticaria usually affects the epidermis and upper layer of the dermis
  • It is mediated by mast cells which cause the release of multiple vasodilatory mediators locally, including histamine
  • Characterized by sudden appearance of wheals (hives) and/or angioedema
  • Intensity of pruritus varies but may be severe enough to disrupt sleep, work or school
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