Use of the oral antiandrogen chlormadinone at a low dose led to improvements in persistence rate of active surveillance (AS), PSA* and testosterone levels and prostate volume, and quality of life (QoL) in men with low-risk prostate cancer (PCa), the PROSAS study has shown.
Long-term exposure to 5-alpha reductase inhibitors (5-ARIs) is not associated with impaired detection of significant cancer on magnetic resonance imaging (MRI) but appears to influence the ability of apparent diffusion coefficient (ADC) metrics to discriminate between lesions harbouring significant and benign cancers, reveals a study.
Postoperative infection is one of the most common complications of radical cystectomy, but preoperative immunonutrition with an L-arginine-based supplement appears to significantly reduce such risk, according to a study.
For patients undergoing robotic radical cystectomy with extracorporeal urinary diversion, the use of antibiotic-irrigating wound protector helps lower the rate of infectious complications, according to a study.
Men with depression appear to have poor semen quality parameters, including volume, concentration, count, and motility, a study has found. Furthermore, the association between depression and semen quality does not seem to be mediated by oxidative stress.