Spatially related clusters of urothelial carcinoma (UC) appear to correlate with locoregional environmental exposures rather than tobacco exposure, suggests a study. Such clusters may also be associated with socioeconomic disparities.
Reduced-dose treatment with androgen receptor pathway inhibitors (ARPI) lead to poorer oncological outcomes relative to full-dose regimens in castration-resistant prostate cancer (CRPC), a recent study has found.
Use of the oral antiandrogen chlormadinone at a low dose led to improvements in persistence rate of active surveillance (AS), PSA* and testosterone levels and prostate volume, and quality of life (QoL) in men with low-risk prostate cancer (PCa), the PROSAS study has shown.
Long-term exposure to 5-alpha reductase inhibitors (5-ARIs) is not associated with impaired detection of significant cancer on magnetic resonance imaging (MRI) but appears to influence the ability of apparent diffusion coefficient (ADC) metrics to discriminate between lesions harbouring significant and benign cancers, reveals a study.
Postoperative infection is one of the most common complications of radical cystectomy, but preoperative immunonutrition with an L-arginine-based supplement appears to significantly reduce such risk, according to a study.
For patients undergoing robotic radical cystectomy with extracorporeal urinary diversion, the use of antibiotic-irrigating wound protector helps lower the rate of infectious complications, according to a study.