There is only a slight improvement in prostate cancer detection rate and Gleason grading as a result of obtaining more than one biopsy core per magnetic resonance imaging (MRI) lesion, a study has shown.
Cefiderocol demonstrated noninferiority to imipenem-cilastatin in patients with complicated urinary tract infections (UTIs) and multidrug-resistant Gram-negative infections, according to results of a phase II trial.
Adopting an aggressive prostate biopsy strategy is recommended in men <50 years with prostate-specific antigen ≥1.5 ng/ml, suggests a study. On the other hand, patients with prostate-specific antigen <1.5 ng/ml are not likely to have significant cancer.
Adding local radiotherapy (RT) on top of standard of care (SoC) improved overall survival (OS) in men with newly diagnosed oligometastatic (ie, low disease burden [Tany Nany M1]) prostate cancer (PCa), according to the STAMPEDE* trial presented at ESMO 2018.
Older patients with recurrent urinary tract infections (rUTIs) tend to be more frail than their peers who have nononcologic urologic diagnoses, according to a study. Of note, rUTIs are significantly associated with frailty but not age.
Robotic surgical extirpation has overtaken the adoption of active surveillance in the management of small renal masses, raising concern that the diffusion of robotic technology furthers overtreatment, especially among elderly and comorbid patients, reports a study.
Treatment with transurethral resection plus systemic chemotherapy results in long-term survival in a subset of patients with muscle-invasive bladder cancer, a recent study in the US has shown. However, the best candidates for this approach remains to be determined.
Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
Higher exposure to ticagrelor following myocardial infarction does not appear to contribute to an increased risk of intracranial haemorrhage, which is associated with age and prior cardiovascular morbidities, according to a study.