Eight new endoscopic surgical methods for benign prostatic hyperplasia appear to be better than monopolar transurethral resection of the prostate (TURP) in terms of safety, according to a study. Among these treatments, enucleation methods achieve better maximal flow rate (Qmax) and international prostate symptoms score (IPSS) than vaporization and resection methods.
Urolithiasis-related obstructive uropathy exerts the worst effect on renal outcome in patients with acute kidney disease (AKI), a study has found. Acute pyelonephritis (APN) and elapsed time to release the obstruction are also associated with poor prognosis.
Treatment with the (ADP-ribose) polymerase (PARP) inhibitor olaparib led to a statistically significant and clinically meaningful improvement in radiological progression-free survival (rPFS) vs physician’s choice of new hormonal agent (NHA) enzalutamide or abiraterone + prednisone in men with advanced prostate cancer harbouring certain gene mutations that were identified through genetic testing, the PROfound* trial has shown.
Men who undergo flexible cystoscopy, particularly with a longer dwell time, may benefit from intraurethral lidocaine as it provides significant pain reduction, suggest the results of a meta-analysis. Evidence is lacking for other tested interventions.