Initial active treatment is associated with generally worse long-term self-reported quality of life (QoL) in men with localized prostate cancer compared with those without a diagnosis of the disease, according to a study. Furthermore, radical prostatectomy results in some adverse effects, particularly in relation to sexual outcomes.
Olaparib, a PARP* inhibitor used to treat ovarian and breast cancer, also extends overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC) harbouring at least one mutation in BRCA1, BRCA2, or ATM, according to final report of the PROfound** study presented at ESMO 2020.
Using the standard American Urological Association (AUA) antibiotic prophylaxis for penile prosthesis surgery among diabetic men with erectile dysfunction results in significantly higher likelihood of postoperative device infection and device explantation compared with nonstandard prophylaxis, suggests a recent study.
Durvalumab with or without tremelimumab in the first-line setting does not improve overall survival (OS) over standard-of-care (SoC) chemotherapy in patients with unresectable, locally advanced or metastatic urothelial carcinoma, according to the phase III DANUBE trial.
Children with bladder bowel dysfunction fare well with combined pelvic floor interferential electrical stimulation and muscle exercises, which can lead to a significant decrease in daytime incontinence, urgency, and constipation, as shown in a study.
Dilutional therapy with tolvaptan favourably alters cystine saturation in the urine and increases urine output in patients with cystinuria, as shown in a small study, suggesting the drug’s potential in reducing the recurrence of stones in this population.
Magnetic resonance imaging (MRI) is vital for the detection of high-grade cancer, and a recent study further adds to this data by recommending systematic biopsy in patients with negative MRI and the inclusion of systematic biopsy in those with positive MRI.
Delays in radical prostatectomy due to the novel coronavirus disease (COVID-19) pandemic does not result in adverse pathology, upgrading, nodal metastasis, or use of postsurgery secondary treatments, according to a recent study.
While most patients do not have such concerns, some young men treated for testicular cancer experience sexual dysfunction and other reproductive concerns 2 years after diagnosis, a recent study has found.
Coadministration of DHA and vitamin E supplements results in increased sperm motility, but no significant changes have been observed in sperm morphology and vitality in asthenozoospermic men, a study has shown.