The addition of abobotulinumtoxinA (aboBTX-A) – one of three commercial preparations of botulinum toxin (BTX) type A – to phosphodiesterase type 5 inhibitors (PDE5-Is) or prostaglandin E1 (PGE1) led to favourable outcomes in men with erectile dysfunction (ED), a new study shows.
Ketorolac, a non-steroidal anti-inflammatory drug (NSAID) and cyclooxygenase inhibitor, is effective and safe in preventing catheter-related bladder discomfort (CRBD) in men who have undergone robot-assisted laparoscopic radical prostatectomy (RALP), highlighting its potential role in postoperative CRBD management, a study shows.
Use of the novel penile traction therapy (PTT) device, RestoreX, in combination with injections of collagenase Clostridium histolyticum (CCH), led to significant improvements in penile deformities due to Peyronie’s disease (PD), a study has shown.
The alpha-1 blocker naftopidil facilitated spontaneous expulsion of small ureteral stones in men, highlighting its potential in medical expulsive therapy (MET) for individuals with ureteral stones, a Japanese study has shown.
It is safe to use the RestoreX device for penile traction therapy for 30–90 minutes per day, with no serious adverse events reported, according to a study. The novel device significantly and clinically improves penile curvature and length, as well as erectile function, in men with Peyronie’s disease.
Oral solithromycin may not be a suitable substitute for ceftriaxone plus azithromycin in the first-line treatment of uncomplicated genital gonorrhoea, according to results of the phase III SOLITAIRE-U* trial.
New drug applications approved by US FDA as of 16 - 31 July 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Human papillomavirus (HPV) vaccination significantly reduces the frequency of genital HPV 16 and 18 infections and cervical intraepithelial neoplasia grade 2+ (CIN2+) in young women and shows signs of herd effects with a reduced frequency of anogenital warts in both young women and men, a recent study showed.
Patients undergoing assisted reproduction for non-male factor infertility do not derive greater benefit from intracytoplasmic sperm injection (ICSI) over in vitro fertilization (IVF), according to a study presented at ESHRE 2019.
Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.