Stereotactic body radiotherapy (SBRT) is associated with significantly lower rates of acute gastrointestinal (GI) and genitourinary (GU) toxicities compared with conventional fractionated intensity-modulated radiotherapy (CF-IMRT) in Asian patients with early-stage localized prostate cancer.
Relying on urinary symptoms alone may lead to an inaccurate diagnosis of culture-positive urinary tract infection, according to a recent Singapore study, which also reports that concurrent urine microscopy may improve diagnostic accuracy.
External beam radiation therapy is a standard option for the initial management of men with localized prostate cancer, and a new guideline states that hypofractionation of radiation treatment confers benefits for cost and convenience.
Cefiderocol demonstrated noninferiority to imipenem-cilastatin in patients with complicated urinary tract infections (UTIs) and multidrug-resistant Gram-negative infections, according to results of a phase II trial.
Adding local radiotherapy (RT) on top of standard of care (SoC) improved overall survival (OS) in men with newly diagnosed oligometastatic (ie, low disease burden [Tany Nany M1]) prostate cancer (PCa), according to the STAMPEDE* trial presented at ESMO 2018.
A combination regimen consisting of the immunosuppressant tacrolimus and the herbal extract Tripterygium wilfordii polyglycoside (TWG) may be effective for the treatment of idiopathic membranous nephropathy (IMN), a new study shows.
Long-term therapy with testosterone undecanoate (TU) in hypogonadal men with type 2 diabetes (T2D) may improve glycaemic control and reverse disease progression, as well as induce significant weight loss, according to a study presented at EASD 2018.
The use of the lymphocyte-selective antiproliferative agent mycophenolate mofetil (MMF) in lower doses is as effective as the chemotherapy drug cyclophosphamide in improving kidney function and reducing proteinuria during induction therapy for proliferative lupus nephritis (LN), a Nepalese trial shows.
The selective xanthine oxidoreductase (XOR) inhibitor topiroxostat reduced the serum uric acid (SUA) level of patients with hyperuricaemia and early diabetic nephropathy (DN) with microalbuminuria, preventing the decline in estimated glomerular filtration rate (eGFR), according to the UPWARD* study.
Use of potassium citrate and thiazides appears to improve health-related quality of life (HRQOL) among stone formers across all Wisconsin Stone Quality of Life (WISQOL) domains without increasing the likelihood of gastrointestinal complaints and fatigue or sexual complaints, respectively, reports a study.
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
Eating high amounts of red and processed meat prior to a diagnosis of colorectal cancer appears to be associated with shorter survival time, although a possible weak association cannot be excluded, a study has shown.