Tobacco smoking exposure appears to result in lower neoadjuvant chemotherapy response rates as well as higher overall and cancer-specific mortality, according to a systematic review and meta-analysis. Smoking status is also associated with bladder cancer recurrence after radical cystectomy.
The placement of an absorbable perirectal hydrogel spacer (HS) led to prostate-rectum separation with less rectal irradiation, fewer rectal toxicities, and better bowel-related quality of life (QoL) in men undergoing radiotherapy (RT) for prostate cancer (PCa), a meta-analysis has shown.
A novel hand-powered spinning device, which employs the principles of centrifugal force and a fidget spinner toy, can perform on-site detection of urinary tract infection (UTI) in about 50 minutes and may prove useful in low-resource settings, as reported in a study.
Treatment with vibegron 75 mg once daily effectively lowers micturitions, urgency episodes, and urge incontinence and increases the volume per micturition in patients with symptoms of overactive bladder (OAB), results of an international phase III study have shown. It is also safe and well tolerated.
Sacral neuromodulation (SNM) was not as cost-effective as serial intradetrusor injections of onabotulinumtoxinA (BTX) for the treatment of refractory urgency urinary incontinence (UUI), the ROSETTA* trial has shown.
The addition of enzalutamide to androgen deprivation therapy (ADT) improved overall survival (OS) in men with nonmetastatic castration-resistant prostate cancer (nmCRPC), demonstrated the phase III PROSPER* trial.
Robot-assisted radical cystectomy with intracorporeal urinary diversion comes with lower perioperative blood loss and a shorter recovery period than open cystectomy, according to a recent Singapore study.
Adding the PD-L1 inhibitor avelumab to best supportive care in the maintenance setting yields significant survival benefit compared with best supporting care alone for patients with advanced bladder cancer who have stable disease following first-line platinum-based chemotherapy, an interim analysis of the JAVELIN Bladder 100 study shows.
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Percutaneous coronary intervention (PCI), compared with coronary artery bypass grafting (CABG), in the revascularization of left main coronary artery (LMCA) disease may lead to death, myocardial infarction (MI), or stroke in patients with moderate or severe left ventricular (LV) dysfunction, reveals a study.