Adherence to a low-fat diet is associated with lower serum testosterone levels among men even when controlling for comorbidities, age, body mass index (BMI) and activity levels, according to a US study.
The addition of the oral phosphodiesterase-5 (PDE-5) inhibitor pentoxifylline to sildenafil failed to show benefit in men with erectile dysfunction (ED) with suboptimal response to sildenafil, a Singapore study shows.
A novel low-intensity pulsed ultrasound (LIPUS) holds therapeutic potential in patients with mild-to-moderate erectile dysfunction (ED), restoring erectile function without deleterious consequences—a benefit attributed to the mechanical force of the device that can reverse the pathological changes in the corpus cavernosum, as shown in a recent study.
Dr Dariusz P. Olszyna, a senior consultant at the Division of Infectious Diseases, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the importance of early detection to prevent the spread and complications related to sexually-transmitted infections (STIs).
Eight new endoscopic surgical methods for benign prostatic hyperplasia appear to be better than monopolar transurethral resection of the prostate (TURP) in terms of safety, according to a study. Among these treatments, enucleation methods achieve better maximal flow rate (Qmax) and international prostate symptoms score (IPSS) than vaporization and resection methods.
Treatment with the (ADP-ribose) polymerase (PARP) inhibitor olaparib led to a statistically significant and clinically meaningful improvement in radiological progression-free survival (rPFS) vs physician’s choice of new hormonal agent (NHA) enzalutamide or abiraterone + prednisone in men with advanced prostate cancer harbouring certain gene mutations that were identified through genetic testing, the PROfound* trial has shown.
New drug applications approved by US FDA as of 01 - 15 November 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
The incidence of urolithiasis (kidney/renal stones) depends on geographic, climatic, ethnic, dietary, and genetic factors. Assistant Professor Chua Wei Jin, Senior Consultant, Department of Urology at the National University Hospital in Singapore discusses with Audrey Abella why urolithiasis is an important healthcare problem that requires attention.
Adding the PD-L1 inhibitor atezolizumab to first-line platinum-based chemotherapy significantly prolonged progression-free survival (PFS) compared with chemotherapy alone in patients with metastatic urothelial carcinoma (mUC), according to the IMvigor130* study presented at the ESMO Congress 2019.
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
Anaemia increases mortality risk in heart failure (HF) patients across the ejection fraction (EF) spectrum, a recent study has found. The effect appears to be stronger in preserved (HFpEF) and midrange (HFmrEF) than in reduced (HFrEF) EF disease.