Infertility is defined as failure to achieve pregnancy after one year of regular unprotected intercourse. It is a significant global problem with a prevalence of approximately 1 in 7 couples.1 Male factor is a common diagnostic category, and as a single factor it accounts for approximately 20% of the infertile couples.2, 3
Premature ejaculation (PE) is the most common sexual dysfunction in men, even more so than erectile dysfunction (ED), say experts in the field of men’s health. A survey which polled more than 3500 men and women from nine countries in the region reported that 1 in 3 men experience some form of PE.
Metronomic cyclophosphamide is modestly effective, and may be a safe and non-expensive treatment alternative in hormone-naïve patients with non-metastatic biochemical recurrent prostate cancer, as stated in a prospective single-arm open-label phase II study.