Pathogens behind paediatric febrile urinary tract infections (UTIs) show a satisfactory in vitro susceptibility profile to first-line therapy with a combination of aminopenicillin and β-lactamase inhibitors, a new study has shown.
Extragonadal steroids have significant contributions to the activation of the androgen receptor axis pathway at castration levels of testosterone in patients with recurrent nonmetastatic prostate cancer, suggests a study. In addition, these steroids promote the development of castration resistance following primary local treatment.
Intravesical gemcitabine and docetaxel is an effective and well-tolerated rescue therapy, delivering a durable response in patients with recurrent nonmuscle invasive bladder cancer and a history of bacillus Calmette-Guérin treatment, a recent study has shown.
Use of double internal stents (DIS) in the long term offers durable relief in patients with secondary extrinsic malignant ureteral obstruction (EMUO), reveals a study. DIS avoids the use of external tubes and improves quality of life, making it a valuable alternative to other methods of urinary diversion.
Cabazitaxel is maximally effective against castration-resistant prostate cancer (CRPC) if used early, before disease progression, a recent study has shown. Dosing should be maintained carefully, however, because of the possibility of side effects.
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Acne is a common skin problem seen in primary care. Dr Wong
Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore
shares his insights with Pearl Toh on how to manage acne in the primary care