Ospemifene appears to produce significant improvements in bladder wall thickness and vaginal dryness, as well as reductions in the number of episodes of nocturia and urgency, among others, in women with vulvovaginal atrophy (VVA) and overactive bladder (OAB) symptoms refractory to β3-agonists or antimuscarinic drugs, a study has shown.
About two in three men with prostate cancer are at increased cardiovascular (CV) risk, suggests a recent study. A positive association exists between a plan to use androgen deprivation therapy and baseline CV risk factors, but such link is explained by confounding factors.
Mirabegron add-on therapy is both safe and effective in the treatment of men with overactive bladder symptoms receiving tamsulosin for benign prostatic hyperplasia, according to the results of a randomized, phase IV study.
Platinum-based neoadjuvant chemotherapy appears to be beneficial in patients with bulky regional lymph node metastases from penile cancer, with nearly 50 percent responding to treatment and about 16 percent achieving a pathological complete response, results of a systematic review and meta-analysis have shown.
In patients with type 2 diabetes (T2D), factors such as high body mass index (BMI) and HbA1c, diabetes complications, calcium oxalate and uric acid stone composition contribute to a heightened risk of kidney stone disease recurrence, as reported in a study.
The use of capsule endoscopy (CE) appears to be effective in the diagnosis of iron deficiency anaemia (IDA), yielding a 33.9-percent yield in this study, with 65.8 percent of patients undergoing further workup and 12.7 percent requiring therapeutic intervention.
Eating behaviours have been shown to moderate the relationship between cumulated risk factors in the first 1,000 days and adiposity outcomes at 6 years of age, which underscores modifiable behavioural targets for interventions, reports a study.
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.