Intraprostatic injections of 2-hydroxyflutamide depot formulations are safe and well tolerated and confer antitumour benefits in men with localized prostate cancer, a recent study has shown. In addition, higher doses and better dose distribution are recommended for better anticancer effects.
Robotic, as compared to open, inferior vena cava thrombectomy achieves more favourable perioperative results and similar oncologic outcomes for renal tumours with level I to II inferior vena cava tumour thrombus, suggests a recent study.
Hypofractionated radiation therapy (RT) appears to be more effective than conventionally fractionated RT (CRT) at improving disease-free survival (DFS) in intermediate-risk prostate cancer (PC), a new study has shown.
Preoperative biopsy Gleason grade (4 + 4 vs any Gleason pattern 5) subclassification of high-risk prostate cancer identifies men at highest risk for progression, according to a study. Furthermore, any Gleason 5 on biopsy correlates with a higher risk of metastasis, as well as prostate cancer-specific and overall mortality.
The use of oral androgen receptor inhibitor enzalutamide may benefit chemotherapy-naïve patients with metastatic castration-resistant prostate cancer and low baseline prostate specific antigen irrespective of disease burden, signifying that targeting the androgen receptor signalling pathway is a therapeutic option in similar patients, suggests a recent study.
Wet nights appear to occur with considerable frequency in children with monosymptomatic nocturnal enuresis and normal maximal voided volumes (MVV), with a nocturnal urine production well below their MWV and even <65 percent of estimated bladder capacity, according to a study.
In patients with renal cell carcinoma, mean platelet volume is a highly significant risk factor for recurrence and cancer-specific death, a recent study has found. This parameter enhances the accuracy of the Leibovich prognosis score to better predict long-term outcomes in localized renal cell carcinoma cases following curative surgical resection.
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.