Financial toxicity, a treatment-related financial burden, is a major concern among patients with bladder cancer and is common among younger patients, a recent study has shown. Those who endorse financial toxicity face delays in care and have poorer health-related quality of life (HRQOL), suggesting the critical role of treatment costs in medical decision-making.
A recent phase III study has found that office-based blue light flexible cystoscopy significantly improves the detection of patients with recurrent bladder cancer and is safe for surveillance. Blue light cystoscopy in the operating room also improves the detection of carcinoma in situ and exposes lesions that are missed with white light cystoscopy.
Urothelial carcinoma patients presenting with concomitant carcinoma in situ (CIS) appear to have a worse outcome than those presenting with pure/primary CIS, a recent study has found. This suggests that the two entities must be differentiated in the treatment decision process.
Recovery to preoperative renal function occur within 2 years in a large proportion of patients after undergoing radical nephrectomy for kidney tumours, a recent study has confirmed, adding that recovery is more probable among those with a lower preoperative estimated glomerular filtration rate (EGFR).
There appears to be no link between the risk of adverse pathology at radical prostatectomy (RP) and biopsy core features in low-risk prostate cancer patients, but the relationship is highly sensitive to the definition of adverse pathology, a recent study has shown.
Shockwave lithotripsy (SWL) may increase the risk of repeat stone-related interventions in children with upper urinary tract calculi (UUTC) by twofold, a study has found. Intraoperative stent placement strongly predicts retreatment, potentially serving as a marker for complex cases or planned staged procedures.
Female cyclists do not have significantly worse urinary or sexual function compared with other athletes, a recent study has shown. However, other genitourinary conditions, such as saddle sores and genital numbness, are associated with cycling and may lead to sexual dysfunction.
There appears to be no clear link between smoking intensity and aggressiveness of bladder cancer at presentation, suggests a recent study, which reports only modest increases in aggressive tumours with increasing smoking intensity in former but not current smokers.
Metronomic cyclophosphamide is modestly effective, and may be a safe and non-expensive treatment alternative in hormone-naïve patients with non-metastatic biochemical recurrent prostate cancer, as stated in a prospective single-arm open-label phase II study.