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Metabolic acidosis tied to improvement of urinary continence after neobladder creation

4 days ago

An association exists between the development of metabolic acidosis following ileal neobladder construction and continuous improvement of urinary continence in the early recovery period, reveals a recent study.

Fosfomycin trometamol on par with other antibiotics for treatment of acute uncomplicated cystitis

5 days ago

The clinical and microbiological effectiveness of a single dose of oral fosfomycin trometamol is comparable to that of comparator antibiotics, as is safety, in women with confirmed or suspected acute uncomplicated cystitis, a recent study has shown. Use of fosfomycin trometamol is also associated with high patient compliance.

Eating greens yields no benefit for prostate cancer

Audrey Abella, 5 days ago

Increasing vegetable consumption did not significantly reduce the risk of prostate cancer progression in men with early-stage disease on active surveillance, the MEAL* trial shows, which contradicts clinical guidelines recommending a vegetable-rich diet in this patient setting.

Abobotulinum toxin A injection improves outcomes in neurogenic bladder

06 Feb 2020

Paediatric patients with neurogenic bladder may benefit from intradetrusor abobotulinum toxin A, which has been shown to improve cystometric capacity and maximum neurogenic detrusor overactivity in a recent study. This effect persists over multiple injections.

Piperacillin–tazobactam combo useful for treating ESBL-producing pyelonephritis

Jairia Dela Cruz, 06 Feb 2020

The combination of piperacillin plus tazobactam performs well in the management of nonbacteraemic pyelonephritis caused by extended-spectrum β-lactamase (ESBL)-producing organisms, with rates of symptom resolution and 30-day mortality similar to that achieved with carbapenem, as shown in a recent study.

Tension-free vaginal tape better than polyacrylamide hydrogel for primary stress urinary incontinence

05 Feb 2020

Use of mid-urethral tension-free vaginal tape slings leads to better satisfaction and cure rates in women with primary stress urinary incontinence compared with polyacrylamide hydrogel injection, according to a study. However, complication risks are higher with tension-free vaginal tape.

Update on ADT: Degarelix shows promise in patients with advanced prostate cancer and CVD

26 Nov 2019

The incidence of prostate cancer (PC) and cardiovascular disease (CVD) typically increases with age; therefore, the choice of treatment for PC should take into account a patient’s underlying cardiovascular conditions. In this interview, Professor Laurence Klotz shared his take on androgen deprivation therapy (ADT) options for patients with prostate cancer who are at-risk of CV events.

Uroselective α1A-AR antagonist: A promising agent for the management of BPH

15 Mar 2019

At the Eisai-sponsored tea symposium during the 27th Malaysian Urological Conference at Shangri-La Kuala Lumpur, Professor Osamu Yokoyama highlighted the advantages of silodosin (Urief®, Eisai Inc.) in relieving lower urinary tract symptoms associated with benign prostate hyperplasia.

Immunotherapy promising treatment option for metastatic castrate-resistant prostate cancer

Pank Jit Sin, 03 Sep 2019

Immunotherapy, in the setting of advanced prostate cancer (PCa), may alter the lethal condition of advanced PCa into a chronic disease with significantly longer overall survival (OS), says an expert.

Research sheds light on PARP inhibitor use in mCRPC

Jackey Suen, 06 Mar 2019

The future of poly(adenosine diphosphate–ribose) polymerase (PARP) inhibitors in the treatment of metastatic castration-resistant prostate cancer (mCRPC) is promising in light of encouraging results from recent clinical studies.

Immune-checkpoint inhibitors changing the landscape of bladder cancer management

Dr. Joseph Delano Fule Robles, 04 Mar 2019

Since the approval of immune checkpoint inhibitors (ICIs) as standard of care in the second-line setting for metastatic urothelial carcinoma, new approaches on how clinicians manage this condition are emerging.

Robot-assisted radical cystectomy comparable to open cystectomy for urologic cancers

Dr. Joseph Delano Fule Robles, 22 Feb 2019

Studies have demonstrated that robot-assisted radical cystectomy (RARC) is as effective and has a cost advantage compared with open cystectomy for the management of urologic cancers.

Prostate cancer biomarker research gains momentum, but challenges remain

Jackey Suen, 30 Jan 2019

Recent research has revealed various potential biomarkers for metastatic castration-resistant prostate cancer (mCRPC), but several challenges remain in fully utilizing them in clinical practice.

Nanotechnology structured water shows potential for ED treatment

Audrey Abella, 11 May 2018

Nanotechnology structured water was similarly effective as tadalafil in improving erectile function, suggesting that it could be a potential treatment option for erectile dysfunction (ED), according to a study presented at EAU held in Copenhagen, Denmark.

Vibegron shows potential as OAB treatment

Audrey Abella, 30 Apr 2018

The selective β3-adrenoreceptor (AR) agonist vibegron showed superior efficacy over placebo for overactive bladder (OAB) treatment and was generally well-tolerated, according to a Japanese study presented at EAU 2018.