Urolithiasis-related obstructive uropathy exerts the worst effect on renal outcome in patients with acute kidney disease (AKI), a study has found. Acute pyelonephritis (APN) and elapsed time to release the obstruction are also associated with poor prognosis.
Use of potassium citrate (Kcit) and thiazide diuretics among stone-formers is associated with better health-related quality of life (HRQOL) without increasing the risk of gastrointestinal events, fatigue or sexual complaints, a study reports.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.