Urinary tract infection (UTI) is complicated if the UTI is associated
with factors that increases colonization and decreases therapy
efficacy. Factors may include one or all of the following: Structural or
functional abnormalities of the genitourinary tract; presence of an
underlying disease that interferes with host defense mechanisms or the
patient being immunocompromised; and being infected by a multi-drug
Principles of therapy includes effective antimicrobial antimicrobial therapy, optimal management of the underlying
abnormalities or other diseases & adequate life-supporting measures.