Urinary tract infection (UTI) is complicated if the UTI is associated
with factors that increases colonization and decreases therapy
efficacy. Factors may include one or all of the following: Structural or
functional abnormalities of the genitourinary tract; presence of an
underlying disease that interferes with host defense mechanisms or the
patient being immunocompromised; and being infected by a multi-drug
Principles of therapy includes effective antimicrobial antimicrobial therapy, optimal management of the underlying
abnormalities or other diseases & adequate life-supporting measures.
In women with polycystic ovary syndrome (PCOS), combined oral contraceptive (COC) with spironolactone is more effective than metformin in reducing symptoms while showing a similar safety profile, according to a new randomized clinical trial (RCT).
Women with bipolar disorder have a significant risk of relapse following childbirth, but management of the disorder during pregnancy is complicated by the potential risk mood stabilizers pose to the developing foetus. A recent article has provided updated recommendations of strategies for managing pregnant women with bipolar disorder in order to ensure optimal outcomes for both mother and child.