Acute uncomplicated urinary tract infection (UTI) is one of the most common bacterial infections in adults that may involve the lower or upper urinary tract or both.
Acute uncomplicated cystitis is an infection limited to the lower urinary tract while acute uncomplicated pyelonephritis is an infection that involves the upper urinary tract (renal parenchyma and pelvicaliceal system) that usually has significant bacteriuria.
Recurrent UTI is characterized by 2 culture-proven episodes of uncomplicated and/or complicated UTI in the last 6 months or ≥3 episodes with positive cultures in the last 12 months in patients with no urinary tract structural or functional abnormalities.

Urinary Tract Infection - Uncomplicated References

  1. American College of Obstetricians and Gynecologists. ACOG practice bulletin no. 91: treatment of urinary tract infections in nonpregnant women. Obstet Gynecol. 2008 Mar;111(3):785-794. http://www.losolivosobgyn.com. Accessed 10 Sep 2012. PMID: 18310389
  2. Epp A, Larochelle A, Lovatsis D, et al; Society of Obstetricians and Gynaecologists of Canada. Recurrent urinary tract infection. J Obstet Gynaecol Can. 2010 Nov;32(11):1082-1090. http://www.sogc.org. Accessed 10 Sep 2012. PMID: 21176321
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  6. Vazquez JC, Abalos E. Treatment for symptomatic urinary tract infections during pregnancy. Cochrane Database Syst Rev. 2011(1):CD002256. http://www.ncbi.nlm.nih.gov/pubmed. PMID: 21249652
  7. MedWormhttp://www.medworm.com/rss/index.php/OBGYN/29/http://www.medworm.com/rss/medicalfeeds/specialities/OBGYN.xml
  8. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  9. Scottish Intercollegiate Guidelines Network. SIGN 88: Management of suspected bacterial urinary tract infection in adults. SIGN. http://www.sign.ac.uk. Jul 2012. Accessed 10 Sep 2012.
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  11. Ministry of Health Malaysia. National antibiotic guideline 2014, 2nd edition. Pharmaceutical Services Divisions, Ministry of Health Malaysia. http://www.pharmacy.gov.my. Dec 2014. Accessed 16 Jul 2015.
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  13. Bonkat G, Pickard R, Bartoletti R, et al. Urological infections. European Association of Urology. http://uroweb.org. 2017. Accessed 06 Apr 2017.
  14. Santoso BI. Tatalaksana. In: Santoso BI. Pedoman Nasional Pelayanan Kedokteran (PNPK) untuk Infeksi saluran kemih (ISK) pada kehamilan. 1st edition. Jakarta: Indonesia Urogynecology Association; 2015:17-22.
  15. Choe HS, Lee SJ, Yang SS, et al; Committee for Development of the UAA-AAUS Guidelines for UTI and STI. Summary of the UAA-AAUS guidelines for urinary tract infections. Int J Urol. 2018 Mar;25(3):175-185. doi: 10.1111/iju.13493. PMID: 29193372
  16. Hooton TM, Gupta K. Acute uncomplicated cystitis in women. UpToDate. https://www.uptodate.com. 06 Dec 2017.
  17. National Antibiotic Guidelines Committee. DOH national antibiotic guidelines 2017. Research Institute for Tropical Medicine. http://ritm.gov.ph. 2017. Accessed 19 Apr 2018.
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  19. Bonkat G, Bartoletti RR, Bruyère F, et al. Urological infections. European Association of Urology (EAU). https://uroweb.org. 2020. Accessed 07 Apr 2020.
  20. Nicolle LE, Gupta K, Bradley SF, et al. Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America. Clin Infect Dis. 2019 Mar 21;pii: ciy1121. doi: 10.1093/cid/ciy1121. PMID: 30895288
  21. Hooton TM, Gupta K. Acute complicated urinary tract infection (including pyelonephritis) in adults. UpToDate. https://www.uptodate.com. 21 Aug 2019. Accessed 23 Apr 2020.
  22. Hooton TM, Gupta K. Acute simple cystitis in women. UpToDate. https://www.uptodate.com. 21 Aug 2019.
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