Acute uncomplicated urinary tract infection (UTI) is one of the most common bacterial infections in adults that may involve the lower or upper urinary tract or both.
Acute uncomplicated cystitis is an infection limited to the lower urinary tract while acute uncomplicated pyelonephritis is an infection that involves the upper urinary tract (renal parenchyma and pelvicaliceal system) that usually has significant bacteriuria.
Recurrent UTI is characterized by ≥2 culture-proven episodes of uncomplicated and/or complicated UTI in the last 6 months or ≥3 episodes with positive cultures in the last 12 months in patients with no urinary tract structural or functional abnormalities.
The oral prodrug tebipenem pivoxil hydrobromide (TBP-PI-HBr) was as effective as intravenous ertapenem in clearing infection and achieving clinical cure in adult patients hospitalized with complicated urinary tract infection (cUTI) and acute pyelonephritis (AP), shows a head-to-head comparison study, ADAPT-PO.
A novel hand-powered spinning device, which employs the principles of centrifugal force and a fidget spinner toy, can perform on-site detection of urinary tract infection (UTI) in about 50 minutes and may prove useful in low-resource settings, as reported in a study.
Pregnant women with urinary tract infections (UTIs) caused by multidrug-resistant (MDR) bacteria may be at increased risk of developing pyelonephritis, according to a single-centre, retrospective study presented at SMFM 2020.
A 3-day course of pivmecillinam to treat uncomplicated lower urinary tract infection (UTI) yielded similar outcomes as a 5-day course, suggesting that 3-day treatment may be sufficient, according to a study from Denmark.
Infection could be a risk factor for stroke, with the risk for ischaemic stroke particularly high among individuals who had a urinary tract infection (UTI) 7 days prior, according to a recently published report.
Catching any type of infection, including those that affect the urinary and respiratory tracts and sepsis, could increase the chances of having subsequent acute ischaemic stroke, according to a recent study.
The four-valent ExPEC4V vaccine which contains O-antigens from the Escherichia coli (E. coli) serotypes O1A, O2, O6A, and O25B was well tolerated and immunogenic against extra-intestinal pathogenic E. coli (ExPEC) infections, according to the phase II US-based ESTELLA trial.
Many patients prescribed antibiotics for suspected urinary tract infection (UTI) in the emergency department (ED) may not actually require them, according to a single-centre study from the UK presented at ECCMID 2019.
Despite a potentially lower risk of treatment failure, prescribing ciprofloxacin or cefalexin for elderly adults presenting with a urinary tract infection (UTI) at a primary care facility may not reduce their risk of sepsis-related hospitalizations, a recent study from the UK showed.
Patients with coronavirus disease 2019 (COVID-19) who have haematologic malignancies have a 28 percent mortality rate, according to data collected from 250 patients by the ASH Research Collaborative COVID-19 presented at the 62nd American Society of Hematology Annual Meeting and Exposition (ASH 2020).
An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.
People are more likely to follow social distancing measures for the novel coronavirus disease (COVID-19) pandemic when they thought that their friends and family did the same, too, according to a new study.