Urinary tract infection (UTI) is complicated if the UTI is associated
with factors that increases colonization and decreases therapy
efficacy. Factors may include one or all of the following: Structural or
functional abnormalities of the genitourinary tract; presence of an
underlying disease that interferes with host defense mechanisms or the
patient being immunocompromised; and being infected by a multi-drug
Principles of therapy includes effective antimicrobial antimicrobial therapy, optimal management of the underlying
abnormalities or other diseases & adequate life-supporting measures.
Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
Treatment with two investigational, oral JAK inhibitors may be beneficial in individuals with moderate‐to‐severe alopecia areata (spot baldness), an autoimmune disease that can cause a lot of anxiety, according to an ongoing phase II study.
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.