Tuberculosis (TB) is caused by Mycobacterium tuberculosis, a gram-positive bacteria with slow growth rate that is enhanced by 6-8% carbon dioxide and temperature of 35-40ºC.
It is primarily transmitted through airborne route.
The number of tubercle bacilli expelled in the air by a TB infected person is directly related to their infectiousness.
TB transmission is rare in children <10 years old due to their inability to expectorate sputum and low TB bacilli load in their sputum.
TB infection in children is usually obtained from an infectious adolescent or adult depending on the closeness and length of contact and the index case's severity of lung involvement and infectiousness.
The addition of lidocaine to intramuscular amikacin lessens pain immediately after injection in children with multidrug-resistant (MDR) tuberculosis (TB), according to a new study. In addition, coadministration of lidocaine does not alter amikacin area under the concentration time curve or maximum plasma concentration.
The use of shorter treatment regimens in children with tuberculosis (TB) infection leads to increased rates of completion and fewer adverse events when compared with 9 months of daily isoniazid treatment, a study has shown.
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April 17 marks World Haemophilia Day, and this year’s theme is “Reaching Out – The First Step to Care”. Adjunct Assoc Prof Joyce Lam Ching Mei, head of the Haematology Laboratory and Blood Bank and senior consultant from the Paediatric Haematology/Oncology Service at KK Women’s and Children’s Hospital, Singapore, speaks to Elaine Soliven on the importance of recognizing and managing bleeding disorders in primary care.
Preterm infants with very low birth weight (VLBW) who were breastfed have significantly higher levels of metabolites important for brain growth and development in their brain tissue compared with formula-fed infants, suggesting that breastfed infants have improved cerebral metabolism at term-equivalent age, according to a study presented at the PAS 2019 Meeting.