Tics are sudden, rapid, non-rhytmic, repetitive, motor movements or vocalizations. The mean age of onset is approximately 5 years old.
Tourette's syndrome is the most common form of tic disorder.
There is a strong genetic component showing a 10- to 100-fold increase
in the rates of tics and Tourette's syndrome among first-degree
relatives of Tourette's syndrome patients.
Simple motor tics are restricted to a single or a few muscle groups and last less than a fraction of a second.
Complex motor tics involve larger muscle groups, usually last longer and appear purposeful and goal-directed.
A new combination product (AXS-07), which consists of the triptan rizatriptan and the NSAID* meloxicam, led to rapid and sustained pain relief than treatment with either component alone or placebo in patients with a history of inadequate response to prior acute migraine treatment, according to data from the MOMENTUM study released during the AAN 2020 Meeting.
While aducanumab significantly reduced clinical decline in individuals with early Alzheimer's disease (AD) in one randomized trial, no changes were seen in another identical study — rendering the role of aducanumab in AD inconclusive.