Most Read Articles
Elaine Soliven, 20 May 2020
Early treatment with a triple antiviral combination of lopinavir-ritonavir, ribavirin, and interferon beta-1b significantly shortens the duration of virus shedding and reduces symptoms in patients with mild-to-moderate COVID-19 compared with lopinavir-ritonavir only, according to a recent study.
Pearl Toh, 26 Sep 2019
The Singapore Health Sciences Authority (HSA) has recalled eight brands of ranitidine products containing trace amounts of the nitrosamine impurity NDMA*, which is a potential human carcinogen.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 14 Apr 2020
With the movement control order (MCO) in full gear, most conferences and meetings are being postponed or cancelled. Some have taken to having conferences and meetings in a virtual setting, such as the recently ended American College of Cardiology/World Congress of Cardiology (ACC.20/WCC) conference. MIMS and the Asian Young Pharmacist Group (AYPG) took this opportunity to engage with pharmacists in the form of a Zoom meeting. 

Zinc acetate lozenge found lacking in common cold treatment

29 Feb 2020

Using a commercially available zinc acetate lozenge for 5 days in the treatment of common cold does not appear to have any effect, according to a study from Finland.

A total of 253 adults who usually had ≥1 cold per winter were randomized to receive a package of zinc (13 mg) or placebo (sucrose octa-acetate) lozenges to be taken in the event of catching the common cold. The participants were instructed to take the lozenges six times daily for a maximum of 5 days.

Eighty-eight of them contracted the disease, among whom 87 (median age, 49 years; 90 percent female) were included in the primary analysis (45 in the active arm; 42 in the placebo arm). The primary outcome of recovery from the common cold during the 10-day follow-up was similar between the zinc vs placebo arms (rate ratio, 0.68, 95 percent confidence interval [CI], 0.42–1.08; p=0.10).

Likewise, the recovery rate for the two groups did not differ during the 5-day intervention, but participants who took zinc showed a significantly slower recovery than those on placebo (p=0.003).

In terms of safety, the absence of adverse effects was noted in fewer participants in the zinc arm (37 percent vs 69 percent).

The researchers acknowledged that it remains uncertain whether the null finding indicates overall lack of efficacy, the daily dose was too low, or the duration of the treatment was too short.

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Most Read Articles
Elaine Soliven, 20 May 2020
Early treatment with a triple antiviral combination of lopinavir-ritonavir, ribavirin, and interferon beta-1b significantly shortens the duration of virus shedding and reduces symptoms in patients with mild-to-moderate COVID-19 compared with lopinavir-ritonavir only, according to a recent study.
Pearl Toh, 26 Sep 2019
The Singapore Health Sciences Authority (HSA) has recalled eight brands of ranitidine products containing trace amounts of the nitrosamine impurity NDMA*, which is a potential human carcinogen.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 14 Apr 2020
With the movement control order (MCO) in full gear, most conferences and meetings are being postponed or cancelled. Some have taken to having conferences and meetings in a virtual setting, such as the recently ended American College of Cardiology/World Congress of Cardiology (ACC.20/WCC) conference. MIMS and the Asian Young Pharmacist Group (AYPG) took this opportunity to engage with pharmacists in the form of a Zoom meeting.