Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.

Younger persons with chronic conditions at higher risk of heart failure

29 Jun 2020

The prevalence of several chronic conditions is higher in patients with heart failure (HF) than population controls, suggests a recent study. Such associations are also seen in those with reduced and preserved ejection fraction, except for hypertension, which is more strongly associated with HF with preserved ejection fraction.

In addition, some cardiometabolic risk factors demonstrate a more robust association with HF in younger individuals, which highlights the importance of optimizing prevention and treatment of risk factors, particularly cardiometabolic risk factors.

In this study, the authors estimated the prevalence of 17 chronic conditions in 2,643 patients with incident HF from 2000 to 2013 and in controls matched 1:1 on sex and age from Olmsted County, Minnesota, in the US. Associations of each condition with HF were determined using logistic regression.

A total of 2,643 matched pairs (mean age, 76.2 years; 45.6 percent men) were included. The comorbidities with the largest attributable risk of HF were arrhythmia (48.7 percent), followed by coronary artery disease (CAD; 33.9 percent) and hypertension (28.4 percent); collectively, these conditions explained 73.0 percent of HF.

Similar associations were found for patients with reduced and preserved ejection fraction, except for hypertension. HF risk attributable to hypertension was twofold higher in HF patients with preserved ejection fraction (38.7 percent) than in those with reduced ejection fraction (17.8 percent).

Of note, the association of HF with hypertension, CAD, arrhythmia, and diabetes were more evident in younger (≤75 years) than in older (>75 years) persons.

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Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.