Wrist circumference tied to elevated SBP in overweight/obese children, adolescents
In overweight/obese children and adolescents, wrist circumference is not only a marker of insulin resistance but is also correlated with elevated systolic blood pressure (SBP), a recent study has shown.
The study included 1,133 overweight or obese children and adolescents who were not previously diagnosed with diabetes mellitus or other endocrine diseases. The effect of wrist circumference and other independent variables on SBP and diastolic BP (DBP) was assessed using multivariate regression analysis.
Males (n=580; mean age 10.5±2.22 years) and females (n=553; mean age 10.0±2.97 years) had statistically similar SBP (110.0±14.86 vs 110.0±14.83 mm Hg) and DBP (70.0±14.81 vs 70.0±14.83 mm Hg). Mean wrist circumference was significantly higher in males (16.0±1.41 vs 15.3±1.14; p<0.0001).
Hypertension was significantly more common in females, with a prevalence rate of 28.2 percent, compared with 22.6 percent in males (p=0.048).
In males, SBP showed a significantly positive correlation with wrist circumference, according to multivariate regression analysis (β, 2.60±0.64; 95 percent CI, 1.35–3.85; p<0.0001). The same trend was observed in females (β, 2.90±0.74; 1.44–4.37; p<0.0001).
In both cases, DBP showed no significant associations with wrist circumference (β in males, 0.47±0.59; –0.69 to 1.63; β in females, 0.40±0.68; –0.95 to 1.74).
“[I]n this study, we found that wrist circumference is positively associated with SBP in a child and adolescent population with overweight/obesity, confirming the relevant role that insulin resistance has in the pathogenesis and development of hypertension,” said researchers.