Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.

Worse QoL seen in hidradenitis suppurativa than psoriasis patients

24 Nov 2017

It appears that patients with psoriasis have lesser health-related quality of life (HRQoL) burden than those with hidradenitis suppurativa (HS), a recent study has found.

“This study clearly documents the needs of patients with HS and the potential impact of medical, scientific and societal consensus for the development of more effective HS treatments,” the investigators said.

To determine which diseases were associated with more severe HRQoL impairment, the investigators determined and compared weighted averages of each of the following baseline HRQoL measures between HS and psoriasis populations from five clinical trials: Visual Analogue Scale (VAS) for pain, Total Work Productivity Impairment, Dermatology Life Quality Index, EuroQOL 5D VAS and Short Form-36 Health Survey.

Patients with HS had higher scores for VAS-pain (54.3 vs 36.1 percent; p<0.001), Dermatology Life Quality Index (15.3 vs 11.3; p<0.0001), EuroQOL 5D VAS (58.8 vs 50.8; p<0.0002) and Total Work Productivity Impairment (35.4 vs 18.2) than did those with psoriasis. On the other hand, patients with psoriasis had higher Short Form-36 Health Survey scores compared with those with HS (physical, 39.6 vs 49.0; mental, 41.5 vs 47.5; p<0.0001 for both).

These findings should be taken in light of some limitations, such as the use of published summary data instead of patient-level data for the analysis, as well as the comparison of weighted pooled averages.

“Psoriasis and HS exhibit distinct clinical features, but no studies have directly compared the HRQoL in patients with moderate-to-severe manifestations of these conditions,” the investigators said.

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Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.