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Worse QoL seen in hidradenitis suppurativa than psoriasis patients

24 Nov 2017

It appears that patients with psoriasis have lesser health-related quality of life (HRQoL) burden than those with hidradenitis suppurativa (HS), a recent study has found.

“This study clearly documents the needs of patients with HS and the potential impact of medical, scientific and societal consensus for the development of more effective HS treatments,” the investigators said.

To determine which diseases were associated with more severe HRQoL impairment, the investigators determined and compared weighted averages of each of the following baseline HRQoL measures between HS and psoriasis populations from five clinical trials: Visual Analogue Scale (VAS) for pain, Total Work Productivity Impairment, Dermatology Life Quality Index, EuroQOL 5D VAS and Short Form-36 Health Survey.

Patients with HS had higher scores for VAS-pain (54.3 vs 36.1 percent; p<0.001), Dermatology Life Quality Index (15.3 vs 11.3; p<0.0001), EuroQOL 5D VAS (58.8 vs 50.8; p<0.0002) and Total Work Productivity Impairment (35.4 vs 18.2) than did those with psoriasis. On the other hand, patients with psoriasis had higher Short Form-36 Health Survey scores compared with those with HS (physical, 39.6 vs 49.0; mental, 41.5 vs 47.5; p<0.0001 for both).

These findings should be taken in light of some limitations, such as the use of published summary data instead of patient-level data for the analysis, as well as the comparison of weighted pooled averages.

“Psoriasis and HS exhibit distinct clinical features, but no studies have directly compared the HRQoL in patients with moderate-to-severe manifestations of these conditions,” the investigators said.

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Most Read Articles
09 Jan 2019
Despite comparable efficacies, triamcinolone injections appear to be slightly superior over 5-fluorouracil injections for inducing keloid remission, a recent trial has found.
Jairia Dela Cruz, 5 days ago
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
04 Jan 2019
Obstructive sleep apnoea may increase the risk of male-pattern baldness in men with a family history of hair loss, and this association appears to be mediated by low serum transferrin saturation levels related to hypoxia, a study suggests.
5 days ago
Airway type 2 inflammation remains persistent in many asthmatics on inhaled corticosteroids, a new study has shown. These patients tend to be older and have a more severe disease.