Most Read Articles
Jairia Dela Cruz, 10 Sep 2019
Use of aspirin in the primary prevention of cardiovascular disease (CVD) in patients with no prior CVD history yields protection against the risks of acute myocardial infarction (AMI) and ischaemic stroke, but at the expense of an increase of similar magnitude in the incidence of major bleeding, according to the results of a recent meta-analysis presented at the European Society of Cardiology (ESC) Congress 2019 in Paris, France.
Dr Margaret Shi, 6 days ago

A comprehensive model of care delivered by nonphysician health workers (NPHWs), involving primary care physicians and families that was informed by local context, substantially improved blood pressure (BP) control and cardiovascular disease (CVD) risk, according to results of the HOPE 4 trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.

What is the cut-off BP value for pregnant women at risk of masked hypertension?

21 Aug 2019

Having identified the prevalence and increased risk of masked hypertension in pregnant women, a recent study suggests that an office blood pressure (BP) of at least 125/75 mm Hg in the second half of gestation may be appropriate to indicate out-of-office measurements in high-risk pregnancies.

Of the 373 women (mean age, 30±7 years with 32±4 weeks of gestation), 69 (18.5 percent) developed pre-eclampsia or eclampsia. A stepwise increase was seen in the risk for pre-eclampsia or eclampsia through quartiles of systolic office BP (8.8 percent, 13.4 percent, 19.6 percent and 32.3 percent; p<0.001) and diastolic office BP (6.5 percent, 13.7 percent, 19.6 percent and 34.4 percent; p<0.001).

There was a significant increase in odds ratio (OR) through quartiles of systolic (p=0.004) and diastolic (p<0.001) office BP. The significance manifested more between the second and third quartile, with the cut-off point being 125/76 mm Hg.

The prevalence of white-coat hypertension was 3.8 percent and masked hypertension 24.7 percent. Using ambulatory BP monitoring (ABPM), 14 of 61 office hypertensive women were reclassified as having white-coat hypertension and 92 of 312 normotensive women as having masked hypertension.

Furthermore, there was a significant increase in OR for pre-eclampsia or eclampsia in women with masked hypertension.

Absolute risk for pre-eclampsia or eclampsia was comparable between women with office BP <125/75 mm Hg and those with normal ABPM (7.2 percent vs 7.1 percent).

This prospective cohort study included women in the second half of high-risk pregnancies. Participants had their office and ambulatory BP measured, and were divided according to quartiles of office BP and in normotension, white-coat hypertension, masked hypertension and sustained hypertension. The investigators then estimated the risks for pre-eclampsia or eclampsia for each category.

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Most Read Articles
Jairia Dela Cruz, 10 Sep 2019
Use of aspirin in the primary prevention of cardiovascular disease (CVD) in patients with no prior CVD history yields protection against the risks of acute myocardial infarction (AMI) and ischaemic stroke, but at the expense of an increase of similar magnitude in the incidence of major bleeding, according to the results of a recent meta-analysis presented at the European Society of Cardiology (ESC) Congress 2019 in Paris, France.
Dr Margaret Shi, 6 days ago

A comprehensive model of care delivered by nonphysician health workers (NPHWs), involving primary care physicians and families that was informed by local context, substantially improved blood pressure (BP) control and cardiovascular disease (CVD) risk, according to results of the HOPE 4 trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.