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Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
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What are the effects of Ramadan fasting on activity, energy expenditure?

16 May 2018
Ramadan is a demanding religious discipline that not only promotes deeper spirituality but also a healthier lifestyle.

An association exists between Ramadan fasting and reduced activity and sleeping time, suggests a study, adding that no significant change is seen in resting metabolic rate (RMR) and total energy expenditure (TEE).

“Reported weight changes with Ramadan in other studies are more likely to be due to differences in food intake,” the investigators said.

Ramadan fasting did not induce any change in RMR (mean±SD, 1,365.7±230.2 vs 1,362.9±273.6 kcal/d for Ramadan and post-Ramadan, respectively; p=0.713; n=29). However, there was greater RMR in the first week of Ramadan compared with subsequent weeks after controlling for the effects of age, sex and body weight.

The total number of steps walked during Ramadan were significantly lower (n=11; p=0.001). There was also a reduction in overall sleeping time, while different sleeping patterns were observed. In addition, no significant difference was seen in TEE between Ramadan and post-Ramadan (mean, 2,224±433.7 vs 2,121.0±718.5 kcal/d, respectively; p=0.7695; n=10).

To investigate the impact of Ramadan fasting on RMR, TEE and activity, 29 healthy nonobese volunteers (16 women) fasting during Ramadan were recruited. Indirect calorimetry was used to measure RMR. Activity (n=11; five women) and TEE (n=10; five women) in free-living conditions were measured using accelerometers and the doubly labelled water technique, respectively, in subgroups of participants.

Bioelectrical impedance was used to measure body composition. The investigators repeated these measurements after a washout period of 1–2 months after Ramadan. Nonparametric tests were used for comparative statistics.

“Fasting during the month of Ramadan entails abstinence from eating and drinking between dawn and sunset and a major shift in meal times and patterns with associated changes in several hormones and circadian rhythms,” the investigators said.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.