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Web-based intervention promotes weight loss among NAFLD patients

06 Nov 2018

A web-based intervention (WBI) yields similar weight-loss benefits for nonalcoholic fatty liver disease (NAFLD) patients as a traditional group-based intervention (GBI), a recent study has found.

The study included 716 consecutive NAFLD patients (mean age 51.6±12.8 years; 53.5 percent male; 33 percent with type 2 diabetes), of whom 438 received GBI meetings led by physicians, dietitians and psychologists. Those who could not attend GBIs were given a WBI (n=278), which involved interactive games, tests and online contact with the centre.

Participants in the WBI group showed a mean reduction of body mass index (BMI) by 3.4 percent at 6 months, 4.9 percent at 12 months and 5.5 percent at 24 months. The decline was statistically significant (p<0.001). Similar findings were reported for the GBI cohort (3.1 percent, 4.0 percent and 4.2 percent, respectively).

However, while BMI progressively dropped significantly in both groups, no significant between-group difference was observed (p=0.063).

Moreover, weight loss of >10 percent of the initial body weight at the 6-month follow-up was reported in 5 percent and 7 percent of the WBI and GBI groups, respectively. These proportions increased to 13 percent and 11 percent by month 12, and to 20 percent and 15 percent by month 24.

Attrition rates were also significantly higher in the WBI group. The number of cases continuously dropped to 76 percent, 58 percent and 43 percent at months 6, 12 and 24, respectively. In comparison, the corresponding retention rates in the GBI group were 87 percent, 80 percent and 69 percent (p<0.001).

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Most Read Articles
5 days ago

Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.

3 days ago
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
5 days ago
It appears that long-term consumption of fish and omega-3 fatty acid does not influence the risk of incident hypertension in middle-aged and older men, suggests a US study.
3 days ago
The risk factors and outcomes associated with an increased risk of permanent pacing include atrial fibrillation (AF) ablation, multivalve surgery and New York Heart Association (NYHA) functional class III/IV, a recent study has found.