Most Read Articles
28 Jun 2019
Mothers who develop gestational diabetes mellitus (GDM) early on in their pregnancies are more likely to develop complications and require caesarean delivery, a new study has shown.
Pearl Toh, 08 Nov 2019
A smartphone-based app for food coaching can help overweight and obese pregnant women control gestational weight gain, suggests a local study.
Roshini Claire Anthony, 30 Sep 2019

Women who conceive singleton pregnancies following assisted reproductive technology (ART) may have a higher risk of developing gestational diabetes than those who conceive spontaneously, according to results of a systematic review and meta-analysis presented at EASD 2019.

Walking before dinner does not translate to 24-h glucose profile improvements

21 Jul 2019

Doing a single bout of walking before dinner has little to no benefits in terms of 24-hour glucose profiles, with the notable exception of a reduction in glucose during the activity itself, according to the results of the E-Paradigm* study.

A total of 80 participants were assigned to two experimental conditions—exercise and nonexercise (control)–separated by 72 hours in a randomized crossover design. Each condition lasted 2 days, during which standardized meals were provided.

Exercise involved 50 minutes of treadmill walking at 5.0 km/h before the evening meal, whereas control consisted of sitting for 50 minutes. Mean glucose during the 24-hour period following exercise (or sitting), measured using continuous glucose monitoring, was the primary outcome.

Of the participants, 73 completed both exercise and control. However, only 63 participants (mean age, 64 years; 54 percent female) observed complied with the standardized diets and had complete continuous glucose monitoring data. Their mean baseline body mass index [BMI] and HbA1c were 30.5 kg/m2 and 51 mmol/mol (6.8 percent), respectively.

Mean 24-h glucose did not improve with exercise vs sitting (0.03 mmol/L, 95 percent CI, –0.17 to 0.22; p=0.778), but individual differences between conditions ranged from –2.8 to 1.8 mmol/L. Likewise, exercise had no significant effect on fasting glucose, postprandial glucose or glucose variability.

There was a notable reduction in glucose concentrations during the 50 minutes of walking vs sitting (–1.56 mmol/L, –2.18 to –0.95; p<0.001).

Researchers pointed out that the E-Paradigm protocol was feasibly implemented across multiple sites and could be implemented in other settings to evaluate responses among individuals with different characteristics or in response to other exercise interventions.

*Exercise-Physical Activity and Diabetes Glucose Monitoring

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
28 Jun 2019
Mothers who develop gestational diabetes mellitus (GDM) early on in their pregnancies are more likely to develop complications and require caesarean delivery, a new study has shown.
Pearl Toh, 08 Nov 2019
A smartphone-based app for food coaching can help overweight and obese pregnant women control gestational weight gain, suggests a local study.
Roshini Claire Anthony, 30 Sep 2019

Women who conceive singleton pregnancies following assisted reproductive technology (ART) may have a higher risk of developing gestational diabetes than those who conceive spontaneously, according to results of a systematic review and meta-analysis presented at EASD 2019.