Most Read Articles
Roshini Claire Anthony, 3 days ago

The addition of methylprednisolone to standard care* reduced mortality risk in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF), according to a study from China.

05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
Stephen Padilla, 3 days ago
High-flow oxygen is not associated with an increase or a decrease in 30-day mortality, suggesting no benefit in most patients presenting with a suspected acute coronary syndrome (ACS), reports a New Zealand study.

Waist circumference better than BMI for predicting prolonged chronic spontaneous urticaria

28 Jan 2021

Rather than body mass index (BMI), waist circumference (WC) seems to be a better predictor of prolonged chronic spontaneous urticaria (CSU), a new study has found.

A total of 52,667 CSU patients (mean age, 54.5 years; 54.4 percent women) participated in the study, and close to half (42.18 percent; n=22,215) had had CSU for >3 years. Those with high WC (44.59 percent) and BMI (43.43 percent) also tended to have had longer disease durations (p<0.05 for both). Smoking, alcohol use, exercise, and household income all did not seem related to CSU duration.

Multivariable Cox proportional hazards models found that a high WC was a significant risk factor for longer CSU. For instance, men with WC between 90–95 cm, along with women with WC between 85–90 cm were 5-percent more likely to have had a longer disease (hazard ratio [HR], 1.056, 95 percent confidence interval [CI], 1.006–1.109).

Men with WC 95–100 cm and women with WC 90–95 cm likewise saw a significantly greater likelihood of longer disease (HR, 1.082, 95 percent CI, 1.016–1.152). No such effect was found for the topmost category, which comprised men with WC ≥100 cm and women with WC ≥95 cm.

On the other hand, none of the BMI categories could significantly predict the occurrence of CSU >3 years.

All models used the second category (BMI: 18.5–23 kg/m2; WC: 85–85 cm in men, 75–80 cm in women) as a reference and were adjusted for age, sex, and comorbidities, such as hyperlipidaemia, hypertension, and diabetes mellitus.

Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 3 days ago

The addition of methylprednisolone to standard care* reduced mortality risk in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF), according to a study from China.

05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
Stephen Padilla, 3 days ago
High-flow oxygen is not associated with an increase or a decrease in 30-day mortality, suggesting no benefit in most patients presenting with a suspected acute coronary syndrome (ACS), reports a New Zealand study.