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Vitamin D therapy improves female sexual function

03 Dec 2018

Women with deficient vitamin D levels and sexual dysfunction may benefit from vitamin D supplementation, which has been shown to yield improvements in sexual function.

In a recent study, 76 women aged 18-45 years with sexual dysfunction (Female Sexual Functioning Index [FSFI] score <26.55) and a serum 25-hydroxyvitamin D (25(OH)D) level of <30 ng/mL were randomized to receive an intramuscular injection of 300,000 IU cholecalciferol (n=38) or a placebo (n=38). Treatment was administered at baseline and after 4 weeks.

FSFI was evaluated at baseline and then after 4 and 8 weeks, whereas serum 25(OH)D levels and depression symptoms (Beck Depression Inventory) were evaluated at baseline and at 8 weeks.

At week 8, serum levels of 25(OH)D increased by a mean of 14.4 ng/mL in the cholecalciferol group (p<0.001) but not in the placebo group.

Moreover, compared with placebo, cholecalciferol supplementation led to a significant increase in the FSFI score at weeks 4 (19.6 vs 16.3; p=0.002) and 8 (25.0 vs 17.1; p<0.001).

The Beck Depression Inventory score decreased by –21.0 in the cholecalciferol group (p<0.001), while no changes occurred in the placebo group.

Of note, the effect of treatment on sexual function was independent from the observed effect on symptoms of depression.

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Most Read Articles
4 days ago

Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.

2 days ago
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
4 days ago
It appears that long-term consumption of fish and omega-3 fatty acid does not influence the risk of incident hypertension in middle-aged and older men, suggests a US study.
2 days ago
The risk factors and outcomes associated with an increased risk of permanent pacing include atrial fibrillation (AF) ablation, multivalve surgery and New York Heart Association (NYHA) functional class III/IV, a recent study has found.