Most Read Articles
Elaine Soliven, 27 Sep 2017
A second dose of kisspeptin-54 improves oocyte yield in women at high risk of ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment, according to a recent study.
23 Oct 2017
Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
Rachel Soon, 2 days ago

Pharmacists can and should utilize their positions within communities to provide access to an extended range of healthcare services, says an expert.

01 Aug 2017
New drug applications approved by US FDA as of 1 - 15 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Vitamin D reduces pain, infections in palliative cancer patients

14 Sep 2017

Vitamin D supplementation in palliative cancer patients improves pain in the first month and reduces infections in the third month after treatment, a new matched case-control study has shown. Moreover, vitamin D supplementation appears to be safe and well tolerated.

In the study, 39 palliative cancer patients (mean age 62±13 years; 21 females) were given vitamin D supplements per day and showed significantly lower baseline quality of life (QoL), as measured by the Edmonton Symptom Assessment Scale (ESAS), compared with 39 matched untreated controls (5.5 vs 4.1; p=0.02).

ESAS QoL showed slight improvements in the vitamin D group (adjusted mean difference [MD], -1.4; 95 percent CI, -2.6 to -0.21) 1 month after treatment, which resulted in an insignificant difference between the two groups.

Higher number of days on antibiotic therapy in the vitamin D group and a corresponding shorter antibiotic duration in controls led to a decreasing trend of infections in the vitamin D group 1 month after treatment. At 3 months, infections were significantly lower in the vitamin D group than in controls (adjusted MD, -26 percent; -41 to -12 percent).

Vitamin D supplementation did not cause unwanted and adverse side effects, such as hypercalcaemia, in the cancer patients.

All patients enrolled were adults, had incurable cancers regardless of type and serum 25-OHD levels <75 nmol/L. Controls were matched according to age, sex, cancer type and 25-OHD level and were taken from a previous observational study at the same ward. Vitamin D3 supplements (cholecalciferol) were administered at a dose of 4,000 IE per day.

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Most Read Articles
Elaine Soliven, 27 Sep 2017
A second dose of kisspeptin-54 improves oocyte yield in women at high risk of ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment, according to a recent study.
23 Oct 2017
Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
Rachel Soon, 2 days ago

Pharmacists can and should utilize their positions within communities to provide access to an extended range of healthcare services, says an expert.

01 Aug 2017
New drug applications approved by US FDA as of 1 - 15 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.