Most Read Articles
09 Dec 2017
Intravenous (IV) iron is less toxic and more effective compared to oral iron, making it a potential frontline therapy for neonatal iron deficiency anaemia, suggests a recent study.
Shilpa Kolhe, MBBS, MD, MRCOG; Shilpa Deb, MBBS, DGO, MRCOG, 01 Aug 2012

Dysmenorrhoea is a medical condition characterized by severe uterine pain during menstruation manifesting as cyclical lower abdominal or pelvic pain, which may also radiate to the back and thighs. The term dysmenorrhoea is derived from the Greek words ‘dys’ meaning difficult, painful or abnormal, ‘meno’ meaning month, and ‘rrhea’ meaning flow. It is commonly divided into primary dysmenorrhoea, where there is no coexistent pathology, and secondary dysmenorrhoea where there is an identifiable pathological condition known to contribute to painful menstruation. Symptoms of primary dysmenorrhoea begin a few hours before the start of menstruation and are often relieved during the first few days of bleeding. The initial onset of primary dysmenorrhoea is usually shortly after menarche (6–12 months), when ovulatory cycles are established. Secondary dysmenorrhoea can also occur at any time after menarche but is most commonly observed in women in their third and fourth decade of life in association with an existing condition.

02 Dec 2014
Adolescent females often experience menstrual problems, and these are usually related to mood changes. In this study, the association between dysmenorrhea and depressive symptoms, anxiety, and premenstrual syndrome was examined.
26 Feb 2017
Placement of cervical pessary in women with short cervices and singleton pregnancies does not lower the risk of having preterm births, according to the results of a meta-analysis.

Vitamin D deficiency linked to preterm births

20 Mar 2017

Vitamin D insufficiency is associated with the risk of preterm births, a new meta-analysis reports. However, there is little evidence to link stillbirths and spontaneous abortions to vitamin D levels.

PubMed and Scopus were searched for original, longitudinal epidemiologic studies regarding vitamin D status and adverse pregnancy outcomes. Only those conducted in humans and those that assessed vitamin D levels through laboratory methods were included.

Studies involving nonsingleton pregnancies and mothers with conditions like HIV and pre-eclampsia were excluded. The Newcastle-Ottawa Scale was used to evaluate the methodological quality of the studies selected.

A total of 18 studies were included. Of these, eight were of very high quality, three had high quality, four had satisfactory quality and three had low quality. Because vitamin D levels were measured through laboratory techniques, the risk of information bias was low.

There was an 83-percent (95 percent CI, 1.23 to 2.74) increased risk of preterm births at <32 to 34 weeks and a 13-percent increased risk (0.94 to 1.36) at <35 to 37 weeks associated with serum 25(OH)D levels <75 nmol/l.

Decreasing levels of serum 25(OH)D was associated with significant increases in the risk of preterm births (50 to 75 nmol/l: summary relative risk [RR].1.25; 1.04 to 1.49; <50 nmol/l: summary RR, 1.36; 1.04 to 1.78).Furthermore, an 11-percent increased risk of spontaneous preterm births at <35 to 37 weeks was associated with serum 25(OH)D levels of<75 nmol/l (RR, 1.11; 0.75 to 1.65).

The risk of stillbirths (RR, 1.02; 0.96 to 1.09), spontaneous abortions (RR, 1.04; 0.95 to 1.13), short gestational lengths (effect size [ES], -0.24; -0.69 to 0.22) and low Apgar scores were not associated with vitamin D insufficiency.

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Most Read Articles
09 Dec 2017
Intravenous (IV) iron is less toxic and more effective compared to oral iron, making it a potential frontline therapy for neonatal iron deficiency anaemia, suggests a recent study.
Shilpa Kolhe, MBBS, MD, MRCOG; Shilpa Deb, MBBS, DGO, MRCOG, 01 Aug 2012

Dysmenorrhoea is a medical condition characterized by severe uterine pain during menstruation manifesting as cyclical lower abdominal or pelvic pain, which may also radiate to the back and thighs. The term dysmenorrhoea is derived from the Greek words ‘dys’ meaning difficult, painful or abnormal, ‘meno’ meaning month, and ‘rrhea’ meaning flow. It is commonly divided into primary dysmenorrhoea, where there is no coexistent pathology, and secondary dysmenorrhoea where there is an identifiable pathological condition known to contribute to painful menstruation. Symptoms of primary dysmenorrhoea begin a few hours before the start of menstruation and are often relieved during the first few days of bleeding. The initial onset of primary dysmenorrhoea is usually shortly after menarche (6–12 months), when ovulatory cycles are established. Secondary dysmenorrhoea can also occur at any time after menarche but is most commonly observed in women in their third and fourth decade of life in association with an existing condition.

02 Dec 2014
Adolescent females often experience menstrual problems, and these are usually related to mood changes. In this study, the association between dysmenorrhea and depressive symptoms, anxiety, and premenstrual syndrome was examined.
26 Feb 2017
Placement of cervical pessary in women with short cervices and singleton pregnancies does not lower the risk of having preterm births, according to the results of a meta-analysis.