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01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Tristan Manalac, Yesterday
While antibody titres against SARS-CoV-2 wane with time, the immune system is capable of producing memory B-cells that can last for at least 6 months after infection, suggesting that the body will be able to protect itself in the case of re-exposure, according to a new study.
Jairia Dela Cruz, 5 days ago
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.

Virtual reality may boost functional mobility in older people

30 Nov 2020

A meta-analysis suggests that virtual reality therapy helps older adults improve their functional mobility as compared with conventional interventions, although the quality of evidence is low.

The meta-analysis included 18 studies that examined the effects of video game consoles with exergames (VRT-NS) and virtual reality equipment designed specifically for rehabilitation programmes (VRT-S) against conventional or no therapy on functional mobility in community-dwelling people aged >60 years.

The total population comprised 568 individuals (71 percent female) with a mean age of 60–96 years. These participants had walking independence, normal cognitive performance, sufficient visual capacity to participate in rehabilitation sessions, and no disability caused by neurological disorders, osteoarticular diseases, severe heart disease, or brain injury.

Four studies used VRT-S, while the rest utilized VRT-NS with low-cost devices such as Nintendo Wii and Sony Play Station. Comparators included traditional rehabilitation, activities of daily living, health education programmes, cycling exercises, and no intervention.

Pooled data revealed VRT-NS to be more effective in increasing functional mobility than no intervention (standardized mean difference [SMD], –1.02, 95 percent confidence interval [CI], −1.91 to −0.14). On the other hand, VRT-NS proved better than CT at improving resistance in ambulation (SMD, −1.20, 95 percent CI, –1.93 to 0.46).

Of note, the beneficial effects of VRT were more pronounced in programmes with >18 sessions (SMD, −0.89, 95 percent CI, –1.71 to –0.08; p<0.001) than in those with less sessions (≤18; SMD, 0.04, 95 percent CI, –0.51 to 0.59) relative to no intervention.

However, the results are inconclusive due to the high risk of bias and the low quality of the GRADE evidence.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Tristan Manalac, Yesterday
While antibody titres against SARS-CoV-2 wane with time, the immune system is capable of producing memory B-cells that can last for at least 6 months after infection, suggesting that the body will be able to protect itself in the case of re-exposure, according to a new study.
Jairia Dela Cruz, 5 days ago
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.