Vaccination not linked to subdural haematomas in babies
There appears to be no temporal link between vaccination and the development of subdural haematomas in infants, a recent study has found.
Researchers performed a prospective, population-based study on 228 infants who had received a vaccine shot. Computerized tomography scan or magnetic resonance imaging was performed to detect the presence of subdural haematoma. Cases were matched with controls based on chronological and gestational age.
Of the participants, 28 were positive for subdural haematomas: 22 had abusive while six had nonabusive head trauma. The remaining 200 children were designated as controls, of whom 61 percent (n=121) had available vaccination information. Majority of those with available vaccine data had received a hexavalent (n=124) pneumococcal (n=123) vaccine; 15 had not received any shots.
After matching, the analysis was carried out in 28 infants with subdural haematomas and in 62 controls without the condition. Cases and controls were not significantly different in terms of the frequency of receiving at least one vaccination since birth (86 percent vs 89 percent; odds ratio [OR], 0.77, 95 percent CI, 0.17–3.86; p>0.50).
The same was true for the frequency of vaccination within the last 7 (11 percent vs 11 percent; OR, 0.94, 0.08–6.96), 14 (18 percent vs 22 percent; OR, 0.70, 0.12–2.92) and 21 (18 percent vs 27 percent; OR, 0.48, 0.08–1.98) days before imaging. Median time since last vaccination (1.4 vs 1.3 months; p=0.62) was comparable in both groups.