Most Read Articles
24 Aug 2016

Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.

26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
Teng Sung Shin, Joyce Lam Ching Mei, 03 Sep 2018
Bleeding disorders in children can be divided into acquired and congenital conditions, with the acquired being far more common than the congenital. Clinical bleeding manifestations can vary in severity. Identifying the root cause early is crucial to control and halt bleeding as well as to prevent the risk of future bleeding in a vulnerable age group. This can be achieved by a thorough and salient history, physical evaluation, and appropriate investigations. This review will describe the common causes of bleeding disorders in children and will suggest an approach to the workup and diagnosis of such disorders.
Rachel Soon, 12 Dec 2018

MIMS Pharmacist presents an overview of superoxide dismutase (SOD) and its role in resisting the effects of oxidative stress and aging.

Use of antiparkinsonian medication tied to acquired premature ejaculation

06 Jun 2018

Individuals taking antiparkinsonian drugs have developed ejaculatory dysfunction, which suggests a possible medication effect, in a case series of Parkinson’s disease (PD) patients with acquired premature ejaculation (PE).

The mean age of PD onset was 53.3±12.7 years (range, 38–77 years), while sexual problems started to appear 4.0±3.1 years later. Patients had a mean 7.3 min (range, 2–20 min) of intravaginal ejaculation latency (IELT) before the onset of acquired PE.

Of note, there was an abrupt appearance of the ejaculatory dysfunction as characterized by a dramatically shortened IELT in all patients. Furthermore, three patients had an ejaculation prior to vaginal penetration, which hampered sexual intercourse.

In some patients, two additional sexual problems occurred: four had erectile dysfunction, five had libido changes, four had increase desire and one had reduced desire.

In this study, the investigators described eight PD patients who asked for a sexological consultation between 2008 and 2014 because of new-onset of PE. Patients were diagnosed with acquired PE according to the DSM-V criteria and the International Society for Sexual Medicine committee. Demographic, medical and sexual-related data of patients were retrieved and analysed.

Acquired PE is defined as “a male sexual dysfunction characterized by the development of a clinically significant and bothersome reduction in ejaculation latency time in men with previous normal ejaculatory experiences, often to about 3 minutes or less, the inability to delay ejaculation on all or nearly all vaginal penetrations, and the presence of negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy.” [Transl Androl Urol 2016;5:434-449]

“PE has been reported in 40.6–51.5 percent of men affected by PD,” the investigators said. “However, this nonmotor sexual complaint has not been studied in detail.”

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Most Read Articles
24 Aug 2016

Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.

26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
Teng Sung Shin, Joyce Lam Ching Mei, 03 Sep 2018
Bleeding disorders in children can be divided into acquired and congenital conditions, with the acquired being far more common than the congenital. Clinical bleeding manifestations can vary in severity. Identifying the root cause early is crucial to control and halt bleeding as well as to prevent the risk of future bleeding in a vulnerable age group. This can be achieved by a thorough and salient history, physical evaluation, and appropriate investigations. This review will describe the common causes of bleeding disorders in children and will suggest an approach to the workup and diagnosis of such disorders.
Rachel Soon, 12 Dec 2018

MIMS Pharmacist presents an overview of superoxide dismutase (SOD) and its role in resisting the effects of oxidative stress and aging.