Most Read Articles
Saras Ramiya, Yesterday
Mundipharma has launched Betadine® Natural Defense personal care product range in Malaysia in collaboration with Watsons.
18 Apr 2018
In patients with rheumatoid arthritis (RA), temporary cessation of methotrexate (MTX) treatment for 2 weeks following influenza vaccination appears to improve the immunogenicity of the vaccine without increasing RA disease activity, according to a study.
Jairia Dela Cruz, 03 May 2018
Acute coronary syndrome (ACS) patients with diabetes mellitus, as well as high-risk nondiabetic patients, appear to obtain significant cardioprotection from the addition of ezetimibe to simvastatin, and this benefit is achieved without compromising safety, according to an exploratory analysis of data from IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).
Saras Ramiya, 15 hours ago
The Malaysian Pharmacy Students’ Association (MyPSA) has successfully organized the 13th National Gathering of Pharmacy Students (NoGAPS) in September.

Ursodeoxycholic acid linked to reduced carotid intima media thickness in NASH

10 Feb 2016
Non-alcoholic steatohepatitis (NASH) patients treated with ursodeoxycholic acid (UDCA) were shown to have reduced mean carotid intima media thickness (CIMT) in a prospective study.

UDCA, which purportedly has antioxidant, anti-inflammatory and hepatoprotective properties, was given to nonhypertensive, nondiabetic, normolipidaemic subjects with biopsy-proven NASH and healthy controls at 15 mg/kg/day for 6 months, to evaluate changes in BMI, waist circumference, homeostasis model assessment, lipids, apo A1, apo B, apo B/A1 ratios, and CIMT. Liver enzymes and the homeostasis model assessment, and Apo B/A1 ratios decreased; high-density lipoprotein (HDL) and apo A1 increased significantly. The mean CIMT decreased significantly. No statistically significant changes were noted in the other parameters.

The authors said the benefit of UDCA is due to decreased insulin resistance and increased HDL and apo A1 levels, but further studies are needed to confirm this.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Pharmacist - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Saras Ramiya, Yesterday
Mundipharma has launched Betadine® Natural Defense personal care product range in Malaysia in collaboration with Watsons.
18 Apr 2018
In patients with rheumatoid arthritis (RA), temporary cessation of methotrexate (MTX) treatment for 2 weeks following influenza vaccination appears to improve the immunogenicity of the vaccine without increasing RA disease activity, according to a study.
Jairia Dela Cruz, 03 May 2018
Acute coronary syndrome (ACS) patients with diabetes mellitus, as well as high-risk nondiabetic patients, appear to obtain significant cardioprotection from the addition of ezetimibe to simvastatin, and this benefit is achieved without compromising safety, according to an exploratory analysis of data from IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).
Saras Ramiya, 15 hours ago
The Malaysian Pharmacy Students’ Association (MyPSA) has successfully organized the 13th National Gathering of Pharmacy Students (NoGAPS) in September.