Most Read Articles
05 May 2019
Statins, when taken before cardiac arrest, improve 1-year survival outcomes, a recent study has found.
Tristan Manalac, 22 Nov 2018
Initial treatment with endovascular therapy results in better amputation-free survival in patients with critical limb ischaemia compared with open surgical bypass, according to a study presented at the American Heart Association Scientific Session 2018 (AHA 2018), held in Chicago, Illinois.
09 May 2019
Cognitive impairments and delirium are frequent postoperative occurrences in patients who undergo coronary artery bypass grafting (CABG) surgery, according to a new meta-analysis.
Tristan Manalac, 29 May 2019
Coronary artery disease is prevalent among patients who have undergone coronary angiography, according to a new Philippine study presented at the recently concluded 2019 Congress of the Asian Pacific Society of Cardiology (APSC 2019). However, the obtained rates remain lower than that in other Asian countries.

Uric acid tied to cardiometabolic risk factors in overweight, obese youths

14 Sep 2018

Uric acid is positively associated with blood pressure, insulin and triglycerides in overweight and obese youths, reports a study. A relevant clustering of metabolic risk factors occur as uric acid levels increase, while the risk factor that is less frequently present is elevated blood pressure (BP).

Among participants, boys had significantly higher uric acid than girls. Uric acid showed a positive, significant association with office, daytime and night-time systolic (S)BP, insulin, and triglycerides.

There was a progressive increment in body mass index (BMI), waist circumference, BMI z score, fasting insulin and HOMA index after stratification by sex-specific uric acid tertiles. Such increment was also observed in office and ambulatory SBP among boys.

Similarly, there was an increase in the number of abnormal metabolic risk factors with the uric acid values. The higher the number of metabolic components, the higher the uric acid values.

Furthermore, multiple regression analysis revealed that uric acid significantly correlated with male sex, waist circumference, both office and night-time SBP, and birth weight.

“Further studies need to assess the mechanistic link between uric acid and the cardiometabolic risk factors,” the authors said.

To examine the link between uric acid and individual cardiometabolic risk factors, as well as their degree of clustering, 333 Caucasians of both sexes (149 women; aged 5–18 years) who underwent an assessment of overweight/obesity were recruited. The authors measured anthropometric parameters, office and 24-hour BP measurement and metabolic profiles, including HDL-cholesterol, triglycerides, insulin, HOMA index and uric acid.

“Observational studies have indicated that high levels of serum uric acid are associated with the risk of cardiovascular disease,” the authors noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
05 May 2019
Statins, when taken before cardiac arrest, improve 1-year survival outcomes, a recent study has found.
Tristan Manalac, 22 Nov 2018
Initial treatment with endovascular therapy results in better amputation-free survival in patients with critical limb ischaemia compared with open surgical bypass, according to a study presented at the American Heart Association Scientific Session 2018 (AHA 2018), held in Chicago, Illinois.
09 May 2019
Cognitive impairments and delirium are frequent postoperative occurrences in patients who undergo coronary artery bypass grafting (CABG) surgery, according to a new meta-analysis.
Tristan Manalac, 29 May 2019
Coronary artery disease is prevalent among patients who have undergone coronary angiography, according to a new Philippine study presented at the recently concluded 2019 Congress of the Asian Pacific Society of Cardiology (APSC 2019). However, the obtained rates remain lower than that in other Asian countries.