Most Read Articles
Jairia Dela Cruz, 10 Sep 2019
Use of aspirin in the primary prevention of cardiovascular disease (CVD) in patients with no prior CVD history yields protection against the risks of acute myocardial infarction (AMI) and ischaemic stroke, but at the expense of an increase of similar magnitude in the incidence of major bleeding, according to the results of a recent meta-analysis presented at the European Society of Cardiology (ESC) Congress 2019 in Paris, France.
02 Feb 2019

High serum concentrations of uric acid correlate with reduced left ventricular ejection fraction among patients with cardiovascular diseases, a recent study has found.

Elvira Manzano, 29 Jun 2019
Cardiovascular (CV) outcomes were similar between the dipeptidyl peptidase 4 (DPP-4) inhibitor linagliptin and the sulfonylurea glimepiride in the CAROLINA* study of patients with early type 2 diabetes (T2D) and increased CV risk.
Dr Margaret Shi, 11 Sep 2019

A comprehensive model of care delivered by nonphysician health workers (NPHWs), involving primary care physicians and families that was informed by local context, substantially improved blood pressure (BP) control and cardiovascular disease (CVD) risk, according to results of the HOPE 4 trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.

Uric acid tied to cardiometabolic risk factors in overweight, obese youths

14 Sep 2018

Uric acid is positively associated with blood pressure, insulin and triglycerides in overweight and obese youths, reports a study. A relevant clustering of metabolic risk factors occur as uric acid levels increase, while the risk factor that is less frequently present is elevated blood pressure (BP).

Among participants, boys had significantly higher uric acid than girls. Uric acid showed a positive, significant association with office, daytime and night-time systolic (S)BP, insulin, and triglycerides.

There was a progressive increment in body mass index (BMI), waist circumference, BMI z score, fasting insulin and HOMA index after stratification by sex-specific uric acid tertiles. Such increment was also observed in office and ambulatory SBP among boys.

Similarly, there was an increase in the number of abnormal metabolic risk factors with the uric acid values. The higher the number of metabolic components, the higher the uric acid values.

Furthermore, multiple regression analysis revealed that uric acid significantly correlated with male sex, waist circumference, both office and night-time SBP, and birth weight.

“Further studies need to assess the mechanistic link between uric acid and the cardiometabolic risk factors,” the authors said.

To examine the link between uric acid and individual cardiometabolic risk factors, as well as their degree of clustering, 333 Caucasians of both sexes (149 women; aged 5–18 years) who underwent an assessment of overweight/obesity were recruited. The authors measured anthropometric parameters, office and 24-hour BP measurement and metabolic profiles, including HDL-cholesterol, triglycerides, insulin, HOMA index and uric acid.

“Observational studies have indicated that high levels of serum uric acid are associated with the risk of cardiovascular disease,” the authors noted.

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Most Read Articles
Jairia Dela Cruz, 10 Sep 2019
Use of aspirin in the primary prevention of cardiovascular disease (CVD) in patients with no prior CVD history yields protection against the risks of acute myocardial infarction (AMI) and ischaemic stroke, but at the expense of an increase of similar magnitude in the incidence of major bleeding, according to the results of a recent meta-analysis presented at the European Society of Cardiology (ESC) Congress 2019 in Paris, France.
02 Feb 2019

High serum concentrations of uric acid correlate with reduced left ventricular ejection fraction among patients with cardiovascular diseases, a recent study has found.

Elvira Manzano, 29 Jun 2019
Cardiovascular (CV) outcomes were similar between the dipeptidyl peptidase 4 (DPP-4) inhibitor linagliptin and the sulfonylurea glimepiride in the CAROLINA* study of patients with early type 2 diabetes (T2D) and increased CV risk.
Dr Margaret Shi, 11 Sep 2019

A comprehensive model of care delivered by nonphysician health workers (NPHWs), involving primary care physicians and families that was informed by local context, substantially improved blood pressure (BP) control and cardiovascular disease (CVD) risk, according to results of the HOPE 4 trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.