Most Read Articles
Roshini Claire Anthony, 2 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 5 days ago
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
07 Nov 2018
The probability of survival in patients with stable ischaemic heart disease (SIHD) increases with more risk factors in control, according to a study.
Pearl Toh, 6 days ago
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Urgent repeat ERCP hints at plastic stent failure

19 Jan 2018
Canadian gambles to save his life and flies to Hong Kong for liver transplant with his wife as living donor.

It appears that urgent repeat endoscopic retrograde cholangiopancreatography (ERCP) predicts failure of plastic stent treatment for biliary strictures (BS) following liver transplant, according to a study.

Overall, 31 patients met the inclusion criteria. Of these, 24 (77.4 percent) resolved with plastic stenting and seven needed surgery.

No significant differences were observed between stent responders and nonresponders with respect to demographics, transplant and postoperative hospitalization data, time from transplantation to presentation with stricture, total number of ERCP sessions, or maximal number of stents.

There was a trend toward a difference in the time elapsed between the first and the second ERCP, in which a second procedure was performed among ERCP nonresponders sooner than responders. Patients who underwent the second procedure as scheduled had a 95-percent endoscopic success rate, while those who presented urgently with acute cholangitis had a 55-percent failure rate (p=0.02).

“This finding may assist earlier triage of these patients toward alternative treatment such as metal stents or surgery, thus sparing needless procedures and complications,” the investigators said.

To identify predictors of response or failure of standard, endoscopic treatment, the investigators performed a retrospective review of the Database of Gastroenterology Department at Tel Aviv Medical Center and analysed data regarding patients who underwent liver transplantation and developed BS.

BS is a common complication of liver transplantation, and the standard treatment is sequential insertion of increasing numbers of plastic stents by ERCP. However, despite high success rates, some strictures fail to resolve and require surgery as definitive treatment, according to the investigators.

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Most Read Articles
Roshini Claire Anthony, 2 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 5 days ago
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
07 Nov 2018
The probability of survival in patients with stable ischaemic heart disease (SIHD) increases with more risk factors in control, according to a study.
Pearl Toh, 6 days ago
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.