Most Read Articles
5 days ago
Living a sedentary lifestyle may increase the risk of cardiovascular diseases (CVD) even in people with healthy body mass index (BMI), reports a new study.
04 Feb 2019
The carbon-chain length of saturated fatty acids appears to be an important factor in determining its role in cardiovascular health, a recent study has found.
3 days ago
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
Jairia Dela Cruz, 04 Feb 2019
Treatment with secukinumab results in a higher rate of remission or low-disease activity at week 16 in patients with psoriatic arthritis as compared with placebo, according to a posthoc analysis of the FUTURE 2 study. This effect is sustained at 2 years and is evident in both tumour necrosis factor inhibitor-experienced and -naïve patients.

Urgent repeat ERCP hints at plastic stent failure

19 Jan 2018
Canadian gambles to save his life and flies to Hong Kong for liver transplant with his wife as living donor.

It appears that urgent repeat endoscopic retrograde cholangiopancreatography (ERCP) predicts failure of plastic stent treatment for biliary strictures (BS) following liver transplant, according to a study.

Overall, 31 patients met the inclusion criteria. Of these, 24 (77.4 percent) resolved with plastic stenting and seven needed surgery.

No significant differences were observed between stent responders and nonresponders with respect to demographics, transplant and postoperative hospitalization data, time from transplantation to presentation with stricture, total number of ERCP sessions, or maximal number of stents.

There was a trend toward a difference in the time elapsed between the first and the second ERCP, in which a second procedure was performed among ERCP nonresponders sooner than responders. Patients who underwent the second procedure as scheduled had a 95-percent endoscopic success rate, while those who presented urgently with acute cholangitis had a 55-percent failure rate (p=0.02).

“This finding may assist earlier triage of these patients toward alternative treatment such as metal stents or surgery, thus sparing needless procedures and complications,” the investigators said.

To identify predictors of response or failure of standard, endoscopic treatment, the investigators performed a retrospective review of the Database of Gastroenterology Department at Tel Aviv Medical Center and analysed data regarding patients who underwent liver transplantation and developed BS.

BS is a common complication of liver transplantation, and the standard treatment is sequential insertion of increasing numbers of plastic stents by ERCP. However, despite high success rates, some strictures fail to resolve and require surgery as definitive treatment, according to the investigators.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
5 days ago
Living a sedentary lifestyle may increase the risk of cardiovascular diseases (CVD) even in people with healthy body mass index (BMI), reports a new study.
04 Feb 2019
The carbon-chain length of saturated fatty acids appears to be an important factor in determining its role in cardiovascular health, a recent study has found.
3 days ago
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
Jairia Dela Cruz, 04 Feb 2019
Treatment with secukinumab results in a higher rate of remission or low-disease activity at week 16 in patients with psoriatic arthritis as compared with placebo, according to a posthoc analysis of the FUTURE 2 study. This effect is sustained at 2 years and is evident in both tumour necrosis factor inhibitor-experienced and -naïve patients.