Most Read Articles
11 Dec 2017
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Tristan Manalac, 4 days ago
Major depressive disorder (MDD) appears to be more prevalent in females than in males, particularly in those who are divorced or widowed, a recent study from Singapore has found.
6 days ago
Tadalafil may not be effective for reducing the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD), as shown in a recent study.
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.

Ultrasound diagnosis of hypospadias in foetus shows high accuracy

09 Apr 2017

Foetal ultrasound diagnosis of hypospadias appears to demonstrate a high positive predictive value for a penile anomaly and a moderately high positive predictive value for the specific diagnosis of hypospadias as compared with a postnatal diagnosis based on physical exam, according to a single-centre retrospective study.

Researchers examined pregnant women who were referred to a foetal care centre and found to carry a foetus with an ultrasound diagnosis of possible hypospadias or who had a new diagnosis of hypospadias after imaging. A total of 32 cases of possible hypospadias were identified.

Results showed that the foetal care ultrasound suggested hypospadias in 78 percent of the 32 suspected cases. Of the 25 cases, 18 were confirmed to have hypospadias on postnatal physical exam, yielding a positive predictive value of 72 percent; and 21 were found to have either hypospadias or another penile anomaly on postnatal physical exam, yielding a positive predictive value for any genital anomaly of 84 percent.

Infants with confirmed hypospadias frequently had several associated genitourinary anomalies on postnatal clinical exam.

An abnormality of anterior urethral and penile development, hypospadias occurs when the urethral folds fail to fuse. The urethral opening is located at a ventral location of the penis, proximal to the tip of the glans penis, which is splayed open. Hypospadias accounts for 68.3 percent of all cases of congenital penile anomalies. Orthoplasty is the best method of treatment, with both ultrasound and foetal MRI being used in diagnosing the foetus. [J Urol 2005;174:1573–1576; Pediatr Surg Int 2015 31:519–527; J Perinat Med 2011;39:451–456; Fetal Diagn Ther 2010;27:164–167]

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Most Read Articles
11 Dec 2017
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Tristan Manalac, 4 days ago
Major depressive disorder (MDD) appears to be more prevalent in females than in males, particularly in those who are divorced or widowed, a recent study from Singapore has found.
6 days ago
Tadalafil may not be effective for reducing the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD), as shown in a recent study.
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.