Most Read Articles
16 Jan 2021
Diagnosis of heart diseases has abruptly and significantly decreased across the globe due to the coronavirus disease 2019 (COVID-19) pandemic, especially affecting poorer countries, reveals a study.
Roshini Claire Anthony, 01 Dec 2020

An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.

Pearl Toh, Yesterday
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.

Ulcers most common cause of gastrointestinal bleeding in COVID-19 patients

30 Oct 2020

Initial presenting symptoms do not differ between coronavirus disease (COVID-19) patients with and without gastrointestinal bleeding (GIB), a recent study has found. In addition, peptic ulcer disease and rectal ulcers from rectal tubes are the most common aetiology of those with upper and lower GIB, respectively.

This matched case-control study included 41 COVID-19 patients with GIB (31 upper and 10 lower) and 82 matched controls of COVID-19 patients without GIB. The investigators characterized bleeding aetiologies and discussed the outcomes and therapeutic approaches involved.

No difference was observed in the presenting symptoms as well as severity of COVID-19 manifestations (p>0.05) of the cases and controls. Ten (32 percent) patients with upper GIB underwent esophagogastroduodenoscopy, and five (50 percent) with lower GIB underwent flexible sigmoidoscopy or colonoscopy.

The most common aetiologies were gastric or duodenal ulcers (80 percent) for upper GIB and rectal ulcers related to rectal tubes (60 percent) for lower GIB. Of the esophagogastroduodenoscopies, four resulted in therapeutic intervention. Three patients with rectal ulcers were subsequently referred to colorectal surgery for rectal packing.

Seven patients who required interventions achieved successful haemostasis. Transfusion requirements did not significant differ between patients who underwent endoscopic therapy and those who were conservatively managed.

Notably, anticoagulation and rectal tube usage appeared to increase the risk for GIB, but the association did not reach statistical significance.

“Conservative management seems to be a reasonable initial approach in managing these complex cases, but larger studies are needed to guide management,” the investigators said.

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Most Read Articles
16 Jan 2021
Diagnosis of heart diseases has abruptly and significantly decreased across the globe due to the coronavirus disease 2019 (COVID-19) pandemic, especially affecting poorer countries, reveals a study.
Roshini Claire Anthony, 01 Dec 2020

An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.

Pearl Toh, Yesterday
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.