Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.

Tubular discectomy on par with microdiscectomy for treatment of lumbar disc herniation

05 Dec 2017

Patients with lumbar disc herniation assigned to tubular discectomy and conventional microdiscectomy show no difference in long-term functional and clinical outcome, a recent study has found.

A total of 325 patients with a symptomatic lumbar disc herniation were randomized to either tubular discectomy (n=166) or conventional microdiscectomy (n=159) to assess the 5-year results of tubular vs microdiscectomy. Researchers performed repeated standardized follow-up measurements at 2, 4, 6, 8, 12, 26, 38, 52, 78, 104, 156, 208 and 260 weeks after randomization.

The main clinical outcomes were as follows: the Roland-Morris Disability Questionnaire for Sciatica (RDQ), Visual Analogue Scale for leg pain and low back pain, self-perceived recovery, and reoperation incidence.

No clinically significant difference was observed between tubular discectomy and conventional microdiscectomy with respect to the main endpoints at any point during the 5 years of follow-up. RDQ scores at 5 years were 4.3 (95 percent CI, 3.3 to 5.2) and 3.4 (2.4 to 4.5) in the tubular discectomy and conventional microdiscectomy group, respectively.

The 0.9 (‒0.6 to 2.2) mean difference was not significant. The mean difference for leg pain was 0.2 (‒5.5 to 6.0) and 0.4 (‒5.9 to 6.7) for back pain.

Complete or near-complete recovery of symptoms was reported in 77 percent of patients in the conventional discectomy group compared with 74 percent in the tubular discectomy group (p=0.79). The reoperation rate was 18 and 13 percent in the tubular and conventional discectomy group, respectively (p=0.29).

“Primary and secondary outcome measures did not support the hypothesized advantages of tubular discectomy over conventional microdiscectomy,” researchers said.

Editor's Recommendations
Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.