Most Read Articles
Roshini Claire Anthony, 23 Nov 2017

The long-term mortality benefit conferred by mechanical over biologic prosthesis in valve replacement appears to be age- and location-dependent, according to findings of a US-based retrospective study.  

10 Jan 2018
Shared decision support with the use of standardized decision aids improves decision quality and reduces implantation of left ventricular assist device as destination therapy (DT-LVAD) in patients with advanced heart failure.
Pearl Toh, 6 days ago
The protective effects of liraglutide against the risks of cardiovascular (CV) events and deaths may be reduced in patients with type 2 diabetes (T2D) who experienced severe hypoglycaemia, but were independent of patient’s history of CV events at baseline, according to post hoc analyses of the LEADER* trial.
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Transthoracic device closure lowers risk of postoperative arrhythmia

29 Sep 2017
Contamination of heater-cooler devices puts patients who undergo open-heart surgery at high risk

Transthoracic device closure (TTDC) seems to reduce the postoperative risk of arrhythmia and is not associated with the risk of other complications, according to a new meta-analysis.

Pooled data from 23 studies (n=4,626) that focused on success rate showed that TTDC resulted in significantly lower rate compared to conventional open-heart surgery (COHS; relative risk [RR], 0.97; 95 percent CI, 0.96 to 0.99; p<0.0001) and case-controls (odds ratio [OR], 0.23; 0.12 to 0.43; p<0.00001).

In terms of intraoperative complications, the case-controls studies showed that TTDC and COHS had comparable rates of intraoperative arrhythmias (OR, 1.18; 0.52 to 2.67; p=0.68). In contrast, cohort studies showed that TTDC significantly decreased the risk of the complication compared with COHS (RR, 0.48; 0.25 to 0.92; p=0.03).

Pooled data from cohort studies also revealed no significant difference in the rates of intraoperative aortic valve insufficiency (RR, 0.89; 0.08 to 9.61; p=0.92) and of residual shunts (RR, 3.39; 0.39 to 4.83; p=0.24) between COHS and TTDC. In case-controlled studies, TTDC had a higher risk of intraoperative residual shunts (OR, 6.98; 1.17 to 41.61 to p=0.03).

Pooled data from four randomized controlled trials found that the risk of postoperative complications was significantly lower for TTDC than COHS (RR, 0.20; 0.13 to 0.32; p<0.00001). The same trend was observed when data from five cohort studies were pooled (RR, 0.50; 0.35 to 0.70; p<0.0001).

In comparison, case-control studies found no significant difference in the risk of postoperative complications (OR, 0.87; 0.42 to 1.79; p=0.71).

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Most Read Articles
Roshini Claire Anthony, 23 Nov 2017

The long-term mortality benefit conferred by mechanical over biologic prosthesis in valve replacement appears to be age- and location-dependent, according to findings of a US-based retrospective study.  

10 Jan 2018
Shared decision support with the use of standardized decision aids improves decision quality and reduces implantation of left ventricular assist device as destination therapy (DT-LVAD) in patients with advanced heart failure.
Pearl Toh, 6 days ago
The protective effects of liraglutide against the risks of cardiovascular (CV) events and deaths may be reduced in patients with type 2 diabetes (T2D) who experienced severe hypoglycaemia, but were independent of patient’s history of CV events at baseline, according to post hoc analyses of the LEADER* trial.
01 Aug 2015
A higher prevalence of coronary artery disease was reported among adult men than women with Kawasaki disease, a study shows.