Most Read Articles
Christina Lau, 02 Jan 2020

Tolvaptan improves dyspnoea, increases sodium levels and reduces body weight in patients with acute heart failure (HF) with or without hyponatraemia, but no significant effect is seen in mortality or rehospitalization, according to a recent meta-analysis.

Pearl Toh, 15 Apr 2020
Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic stenosis who are at low surgical risk appears to be safe with low rates of death or disabling stroke at 30 days, according to a study presented at the ACC.20/WCC Virtual Meeting.

Total radiation higher in obese patients undergoing radiofrequency ablation

24 Sep 2019
Under new NHS criteria, obese patients “will not get non-urgent surgery until they reduce their weight”.

Obese patients are exposed to greater doses of radiation during radiofrequency ablation for atrial fibrillation, a recent study has found.

The study included 144 patients (median age, 60 years; 21 percent female) who received radiofrequency ablation for atrial fibrillation. Most (n=68) of the participants were overweight, while 48 were obese and 34 were normal-weight. The primary endpoint was the cumulative end dose (ED), defined as the sum of doses received during the preprocedural computed tomography and during the ablation procedure.

Both overweight (p=0.2) and obese (p=0.007) patients received higher EDs, with a 23- and 75-percent difference relative to their normal-weight counterparts, respectively. Only the effect on obese patients was statistically significant.

“Impact of obesity on overall exposure to ionizing radiation, which was previously considered to be major with a dose increase of >300 percent for obese patients, seems finally revealed to be moderate,” said researchers.

Multivariate, generalized linear regression analysis found that body mass index was a significant predictor of overall ED received (β per additional kg/m2, 0.27±0.11; p=0.009), as was X-ray time (β per additional minute, 0.27±0.10; p=0.004). Other univariate predictors such as sex, left atrial volume and the type of atrial fibrillation lost their significance after adjusting for covariates.

In addition, BMI was also a significant determinant of the success of the procedure (p=0.04), as were left atrial volume (p<0.001) and the type of atrial fibrillation.

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Most Read Articles
Christina Lau, 02 Jan 2020

Tolvaptan improves dyspnoea, increases sodium levels and reduces body weight in patients with acute heart failure (HF) with or without hyponatraemia, but no significant effect is seen in mortality or rehospitalization, according to a recent meta-analysis.

Pearl Toh, 15 Apr 2020
Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic stenosis who are at low surgical risk appears to be safe with low rates of death or disabling stroke at 30 days, according to a study presented at the ACC.20/WCC Virtual Meeting.