Most Read Articles
Roshini Claire Anthony, 6 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
4 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Topical hydrogen peroxide safe, well-tolerated for seborrheic keratosis

25 Oct 2018

A 40-percent hydrogen peroxide topical solution (HP40) effectively and safely removes seborrheic keratoses (SK), according to a recent study.

In two identical phase 3 pivotal studies, researchers randomly assigned 937 SK patients each with four lesions to receive either HP40 (n=467; mean age 68.3±8.68 years; 61.2 percent female) or vehicle control (n=470; mean age 69.1±8.67 years; 55.7 percent female). The Physician’s Lesion Assessment (PLA) scale was used to grade SKs, and lesions that were graded above zero after initial treatment were retreated 3 weeks later.

Significantly more participants in the HP40 group achieved a PLA score of 0 in all four lesions than in the control group in both the first (4 percent vs 0 percent; p<0.01) and second (8 percent vs 0 percent; p<0.01) pivotal studies. Similar findings were observed for complete clearance in three of four lesions (study 1: 13 percent vs 0 percent; study 2: 23 percent vs 0 percent; p<0.0001 for both).

Notably, 25.0 percent of all SK lesions in the HP40 group achieved a PLA score of 1 after the first treatment.

In terms of safety, pooled analysis of both studies revealed that 21 percent of all HP40 participants reported 145 treatment-emergent adverse events (TEAEs), compared with only 126 TEAEs in 88 patients in the vehicle control group. Most of the TEAEs were either mild or moderate in intensity.

Three TEAEs in the HP40 group were identified as severe and related to the study medication. One case was of pain at the application site, another was of burning from treatment and the final one was of burning sensation.

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Most Read Articles
Roshini Claire Anthony, 6 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
4 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.