Most Read Articles
Saras Ramiya, 4 days ago
US researchers show split liver transplantation and living donor liver transplantation (LDLT) may be superior to whole liver transplantation in improving outcomes in paediatric patients.
27 Nov 2017
Chronic hepatitis B virus (HBV) infection is a global problem. Chronic HBV infection is probably the most common maternal infection encountered in Hong Kong, China, and Southeast Asia. In Hong Kong, which is one of the endemic areas, immunisation against HBV was first provided in 1983 to infants born to mothers who were screened positive for hepatitis B surface antigen (HBsAg). Immunisation became widespread since November 1988, but HBsAg-positive mothers are still encountered frequently.1
01 May 2013

One of the most common eye problems that pharmacists will encounter is red eye. Red eye is a clinical sign and not a diagnosis, just like fever is a symptom and not a diagnosis. A red eye is caused by dilation of conjunctival or ciliary blood vessels in the eye. Conjunctival injection mainly affects the vessels at the posterior part and is seen in conjunctivitis. Ciliary injection involves anterior ciliary arteries and usually is seen in inflammation of the cornea, iris or ciliary body.

Sudeta D Connolly, Sonali Nanayakkara, 01 Aug 2011

Anxiety disorders are one of the most common psychiatric disorders in children and adolescents, but they often go undetected or untreated. Identification and effective treatment of childhood anxiety disorders can decrease the negative impact of these disorders on academic and social functioning in youth and their persistence into adulthood. Because of the national shortage of child and adolescent psychiatrists in the US, paediatricians are increasingly called on to be front-line partners with child mental health professionals to coordinate care—with screening and early identification as well as with multimodal treatment of childhood anxiety disorders.

Thyroid dysfunction tied to poor development in children with iodine excess

02 Dec 2017

In children with chronic excessive exposure to iodine, thyroid dysfunction is associated with impaired development, a recent study shows.

“The high iodine intake may have caused the thyroid dysfunction and hence the delayed developmental status; however, other influential factors cannot be excluded,” said the researchers.

The study included 298 children (median age 31.4 months; 52.3 percent female), in whom urinary iodine concentrations (UIC) were measured.  None of the participants were taking thyroid hormones or had known thyroid disease.

The third edition of the ages and stages questionnaire (ASQ-3) was used to evaluate child development. Thyroid function was assessed using concentrations of the thyroid hormones serum thyrotropin (TSH), free thyroxin and free triiodothyronine.

The median UIC in the cohort was 451.6 µg/L, while the median ASQ-3 score was 180 with scores ranging from 45 to 270.

In the unadjusted models, thyroid disturbance (odds ratio [OR], 0.49; 95 percent CI, 0.25 to 0.95; p<0.05) and having TSH levels outside the reference (OR, 0.40; 0.19 to 0.88; p<0.05) significantly reduced the chances of being in the top two tertiles of ASQ-3 scores. The respective associations were attenuated after adjusting for potential confounders (OR, 0.51; 0.25 to 1.02; p=0.058 and OR, 0.48; 0.22 to 1.08; p=0.075).

Because the general motor subscale of the ASQ-3 was found to have poor discriminatory ability, the researchers repeated the above analysis excluding this domain. Results showed that thyroid disturbance (OR, 0.46; 0.23 to 0.93; p<0.05) and having TSH concentrations outside the reference (OR, 0.42; 0.19 to 0.94; p<0.05) were significantly associated with lower chances of being in the top two tertiles of ASQ-3 scores, even in the adjusted models.

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Most Read Articles
Saras Ramiya, 4 days ago
US researchers show split liver transplantation and living donor liver transplantation (LDLT) may be superior to whole liver transplantation in improving outcomes in paediatric patients.
27 Nov 2017
Chronic hepatitis B virus (HBV) infection is a global problem. Chronic HBV infection is probably the most common maternal infection encountered in Hong Kong, China, and Southeast Asia. In Hong Kong, which is one of the endemic areas, immunisation against HBV was first provided in 1983 to infants born to mothers who were screened positive for hepatitis B surface antigen (HBsAg). Immunisation became widespread since November 1988, but HBsAg-positive mothers are still encountered frequently.1
01 May 2013

One of the most common eye problems that pharmacists will encounter is red eye. Red eye is a clinical sign and not a diagnosis, just like fever is a symptom and not a diagnosis. A red eye is caused by dilation of conjunctival or ciliary blood vessels in the eye. Conjunctival injection mainly affects the vessels at the posterior part and is seen in conjunctivitis. Ciliary injection involves anterior ciliary arteries and usually is seen in inflammation of the cornea, iris or ciliary body.

Sudeta D Connolly, Sonali Nanayakkara, 01 Aug 2011

Anxiety disorders are one of the most common psychiatric disorders in children and adolescents, but they often go undetected or untreated. Identification and effective treatment of childhood anxiety disorders can decrease the negative impact of these disorders on academic and social functioning in youth and their persistence into adulthood. Because of the national shortage of child and adolescent psychiatrists in the US, paediatricians are increasingly called on to be front-line partners with child mental health professionals to coordinate care—with screening and early identification as well as with multimodal treatment of childhood anxiety disorders.