Most Read Articles
11 Sep 2017
An inverse association exists between systolic blood pressure (SBP) in young adults and depression and anxiety score, independent of a range of lifestyle confounders, according to a recent study. Furthermore, the inverse association between SBP and self-reported history of depression is enhanced by adiposity despite a positive correlation between BP and body mass index (BMI).
Dr. Joseph Delano Fule Robles, 04 Sep 2017

A recent genome-wide association study (GWAS) performed by investigators from the Chinese University of Hong Kong (CUHK) has found potential new indications for existing drugs for the treatment of various psychiatric disorders. 

13 Sep 2017
The likelihood of suicidal ideation, suicide attempts and completed suicides is substantially greater in patients with psoriasis, according to a recent study. Among these patients, those who are younger and whose psoriasis is more severe are at risk of suicidality.
Roshini Claire Anthony, 05 Sep 2017

Selective serotonin reuptake inhibitors (SSRIs) may improve gross motor function, disability, and quality of life (QoL) among patients recovering from stroke, according to a systematic review and meta-analysis.

Testing the efficacy of repetitive transcranial magnetic stimulation for acute depression

10 Jan 2017
Different repetitive transcranial magnetic stimulation (rTMS) modalities have minimal differences in clinical efficacy and acceptability for acute depressive disorder, new study shows.

The systematic review and meta-analysis evaluated the response rate, acceptability and remission using different rTMS strategies for treatment of acute depression.

The analysis included 81 randomized trials that assessed rTMS modalities versus sham or another rTMS intervention. A total of 4,233 patients were included. The mean age of the subjects was 46 years and majority were women (59.1%).

Priming low-frequency, bilateral, high-frequency, low-frequency, and θ-burst rTMS were more effective than sham. Accelerated, synchronized, and deep rTMS were less effective than sham.

The rTMS modalities had similar remission response rates, except for θ-burst stimulation. Acceptability was similar for all rTMS interventions.

The most effective and acceptable rTMS strategies were priming low-frequency and bilateral methods.

The investigators concluded that the study results do not have high reliability due to lack of available trials for the different rTMS interventions except for than low-frequency, high-frequency, and bilateral methods.

It is suggested that larger RCTs should evaluate the usefulness of rTMS for treatment of major depressive disorder (MDD). Results also show that novel methods accelerated, synchronized, and deep rTMS may not be effective for MDD.
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Most Read Articles
11 Sep 2017
An inverse association exists between systolic blood pressure (SBP) in young adults and depression and anxiety score, independent of a range of lifestyle confounders, according to a recent study. Furthermore, the inverse association between SBP and self-reported history of depression is enhanced by adiposity despite a positive correlation between BP and body mass index (BMI).
Dr. Joseph Delano Fule Robles, 04 Sep 2017

A recent genome-wide association study (GWAS) performed by investigators from the Chinese University of Hong Kong (CUHK) has found potential new indications for existing drugs for the treatment of various psychiatric disorders. 

13 Sep 2017
The likelihood of suicidal ideation, suicide attempts and completed suicides is substantially greater in patients with psoriasis, according to a recent study. Among these patients, those who are younger and whose psoriasis is more severe are at risk of suicidality.
Roshini Claire Anthony, 05 Sep 2017

Selective serotonin reuptake inhibitors (SSRIs) may improve gross motor function, disability, and quality of life (QoL) among patients recovering from stroke, according to a systematic review and meta-analysis.