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Rachel Soon, 16 Aug 2019

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Tesla multiparametric MRI: Comparing performance with/without endorectal coil in prostate cancer

18 Feb 2019
Unneeded MRI scans for patients with acute lower back pain are one of the contributors to pointless medical costs that burden the government and/or the patient.

Detection of overall and index prostate cancer is comparable in three Tesla multiparametric magnetic resonance imaging (MRI) with and without an endorectal coil, a study has found. However, the endorectal coil subcohort has markedly higher detection of posterior and peripheral prostate cancer, as well as detection of anterior and transition zone prostate cancer.

Overall, 429 patients (mean age 61.8 years) with 871 whole mount histopathology lesions were analysed. The subcohort with an endorectal coil comprised 260 patients and that without one 169 patients, with a corresponding total of 529 and 342 lesions.

The overall tumour detection rate in all patients was 49.6 percent (432 of 871, while that in the endorectal and nonendorectal coil subcohorts was 50.5 percent (267 of 529) and 48.2 percent (165 of 342), respectively. The index tumour detection rates overall and in the endorectal and nonendorectal coil subcohorts were 77.6 percent (333 of 429 patients), 78.5 percent (204 of 260) and 76.3 percent (129 of 169), respectively.

The investigators detected 35.9 percent (66 of 184) and 48.4 percent (76 of 157) of anterior lesions (p=0.019) in the endorectal and nonendorectal coil subcohorts, respectively, as well as 58 percent (200 of 345) and 48.1 percent (89 of 185) of posterior lesions (p=0.025), 37.3 percent (41 of 110) and 54.4 percent (62 of 114) of transition zone lesions (p=0.010), and 53.7 percent (225 of 419) and 45.2 (103 of 228) of peripheral lesions (p=0.033).

Furthermore, the endorectal coil group only showed higher detection of peripheral and posterior prostate cancer after adjusting for clinical and pathological factors.

Patients who underwent three Tesla multiparametric MRI with and without an endorectal coil from July 2009 to December 2016 prior to prostatectomy were included in this retrospective HIPAA* compliant, institutional review board-approved, case-control study.

The investigators calculated the tumour detection rate for total and index lesions and compared lesion MRI and histopathology features between the two groups. Using SPSS version 24, p<0.05 was considered significant.

*Health Insurance Portability and Accountability Act

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Most Read Articles
Rachel Soon, 16 Aug 2019

On 8 August, the first town hall held by the Ministry of Health (MOH) with members of the pharmacy profession took place in Putrajaya. Over 500 pharmacists from across the country and from different areas of practice—community and hospital, public and private, academy and industry—converged to fill the auditorium for the chance to engage in direct dialogue with MOH.

2 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
14 hours ago
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
5 days ago
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.