Most Read Articles
23 Apr 2018
Long‐term treatment with perampanel in the adjunctive setting appears to provide improved seizure control without raising new safety/tolerability signals in patients with epilepsy, particularly those with secondarily generalized seizures at baseline, according to the results of an open-label extension of phase III trials.
Audrey Abella, 20 Mar 2020
The addition of highly purified cannabidiol (CBD) into an antiepileptic regimen led to reductions in convulsive seizure rates in children with Dravet syndrome (DS), the GWPCARE2* study has shown.
27 May 2020
High rather than low levels of neonatal 25(OH)D3 pose an increased risk of incident epilepsy in early childhood, a finding that may be attributed to chance, confounding, or late gestational vitamin D exposure, according to a study.
Jairia Dela Cruz, 29 Jan 2020
In the treatment of idiopathic generalized epilepsy, switching from valproate to other antiepileptic drugs due to potential childbearing issues may prove detrimental, heightening the risk of poor seizure control, as shown in a recent study.

Telemonitoring + telephone-based counselling improves BP in stroke survivors

Elaine Soliven
18 Mar 2020
Dr Gbenga Ogedegbe (copyright to American Heart Association - Photo by Todd Buchanan 2020)

Home blood pressure telemonitoring (HBPTM) combined with telephone-based nurse case management (NCM) led to a greater reduction in systolic blood pressure (BP) among minority stroke survivors with uncontrolled hypertension than HBPTM alone, according to a study presented at ISC 2020.

This study involved 450 stroke survivors (mean age 61.70 years, 44.4 percent women) who were recruited from Comprehensive Stroke Centers and Primary Care Practices of three academic centres and six public hospitals in the US. Participants were randomized to receive either HBPTM alone (BP readings ≥3 days a week; n=226) or HBPTM plus NCM (20 telephone-based counselling sessions by nurses; n= 224) for 12 months. All BP readings were sent to patients and physicians. Patients were followed-up at 6 and 12 months. [ISC 2020, abstract LB19]

At baseline, mean systolic BP was similar between the HBPTM plus NCM and HBPTM alone treatment groups at 150.03 and 148.03 mm Hg, respectively.

Although both treatment groups experienced reductions in systolic BP, patients who received HBPTM plus NCM had a greater reduction in systolic BP than those who received HBPTM alone at 6 months (13.63 vs 6.31 mm Hg; p<0.05) and 12 months (14.76 vs 5.52 mm Hg; p<0.05).

Overall, mean systolic BP was lower in the HBPTM plus NCM group than the HBPTM alone group at 6 months (136.41 vs 141.72 mm Hg) and 12 months (135.27 vs 142.5 mm Hg).

“The magnitude of reduction in systolic BP for those who received lifestyle counselling and support was much larger than we expected … The reduction in systolic BP of 14 mm Hg among these patients would be expected to translate to at least a 20 percent decrease in stroke deaths and 34 percent fewer secondary strokes. These are pretty robust findings,” said lead author Dr Gbenga Ogedegbe from the Department of Population Health at NYU Grossman School of Medicine in New York, US. “[However,] effectiveness of this intervention in secondary stroke prevention warrants further investigation.”

“The results [also] suggest that hypertension management in patients at high risk for recurrent stroke should involve telephone-based lifestyle counselling by a non-physician health worker coupled with HBPTM. The role of the nurse case manager could be played by the patient’s pharmacist or other trained non-physician health workers,” Ogedegbe noted.

“Hypertension, [or uncontrolled BP], is a major predictor of racial disparities in stroke outcomes in the US ... Improved BP control among minority stroke survivors is key to secondary stroke prevention … these findings provide strong empirical evidence for widespread implementation in low-income minority stroke survivors with multiple comorbidity,” he added.
Editor's Recommendations
Most Read Articles
23 Apr 2018
Long‐term treatment with perampanel in the adjunctive setting appears to provide improved seizure control without raising new safety/tolerability signals in patients with epilepsy, particularly those with secondarily generalized seizures at baseline, according to the results of an open-label extension of phase III trials.
Audrey Abella, 20 Mar 2020
The addition of highly purified cannabidiol (CBD) into an antiepileptic regimen led to reductions in convulsive seizure rates in children with Dravet syndrome (DS), the GWPCARE2* study has shown.
27 May 2020
High rather than low levels of neonatal 25(OH)D3 pose an increased risk of incident epilepsy in early childhood, a finding that may be attributed to chance, confounding, or late gestational vitamin D exposure, according to a study.
Jairia Dela Cruz, 29 Jan 2020
In the treatment of idiopathic generalized epilepsy, switching from valproate to other antiepileptic drugs due to potential childbearing issues may prove detrimental, heightening the risk of poor seizure control, as shown in a recent study.